Bioimplant surfaces: binding of fibronectin and fibroblast adhesion

Bioimplant surfaces: binding of fibronectin and fibroblast adhesion

The adhesion of baby hamster kidney 21C/13 fibroblasts to surfaces of passivated titanium, carbon fibers, bioactive glasses B5 and B6, fibronectin-precoated passivated titanium, and fibronectin-precoated B6 was quantified. The order of adhesive cell avidity for the uncoated surfaces was passivated t...

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Veröffentlicht in:Journal of orthopaedic research 1988, Vol.6 (1), p.58-62
Hauptverfasser: CANNAS, M, DENICOLAI, F, WEBB, L. X, GRISTINA, A. G
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biocompatible Materials - pharmacology
Biological and medical sciences
Carbon - pharmacology
Cell Adhesion - drug effects
Cells, Cultured - drug effects
Cricetinae
Fibroblasts - metabolism
Fibroblasts - ultrastructure
Fibronectins - metabolism
Fibronectins - pharmacology
Glass - pharmacology
Kidney - drug effects
Kidney - metabolism
Medical sciences
Mesocricetus
Microscopy, Electron, Scanning
Orthopedic surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Titanium - pharmacology
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Zusammenfassung:The adhesion of baby hamster kidney 21C/13 fibroblasts to surfaces of passivated titanium, carbon fibers, bioactive glasses B5 and B6, fibronectin-precoated passivated titanium, and fibronectin-precoated B6 was quantified. The order of adhesive cell avidity for the uncoated surfaces was passivated titanium (greatest), B6 and carbon fibers (intermediate), and B5 (least). Precoating with fibronectin enhanced the adhesive characteristics of fibroblasts on passivated titanium and B6 by 74% and 118%, respectively.
ISSN:0736-0266
1554-527X
DOI:10.1002/jor.1100060108