Novel 28-kDa secretory protein from rat olfactory epithelium
We have isolated a novel secretory 28-kDa protein which is an abundant component of the rat olfactory mucosa. The partial sequence of the 28-kDa protein has been determined. The amino acid sequence of the 28-kDa protein is similar to that of non-selenium glutathione peroxidase from bovine ciliary bo...
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| Veröffentlicht in: | FEBS letters 1996-02, Vol.381 (1), p.12-14 |
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| container_title | FEBS letters |
| container_volume | 381 |
| creator | Peshenko, I.V. Novoselov, V.I. Evdokimov, V.A. Nikolaev, Yu.V. Shuvaeva, T.M. Lipkin, V.M. Fesenko, E.E. |
| description | We have isolated a novel secretory 28-kDa protein which is an abundant component of the rat olfactory mucosa. The partial sequence of the 28-kDa protein has been determined. The amino acid sequence of the 28-kDa protein is similar to that of non-selenium glutathione peroxidase from bovine ciliary body. The 28-kDa protein catalyzed decomposition of the hydrogen peroxide as well as organic hydroperoxides by reduced glutathion and seems to be a member of the glutathion peroxidases family. |
| doi_str_mv | 10.1016/0014-5793(96)00071-3 |
| format | Article |
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The partial sequence of the 28-kDa protein has been determined. The amino acid sequence of the 28-kDa protein is similar to that of non-selenium glutathione peroxidase from bovine ciliary body. 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The partial sequence of the 28-kDa protein has been determined. The amino acid sequence of the 28-kDa protein is similar to that of non-selenium glutathione peroxidase from bovine ciliary body. The 28-kDa protein catalyzed decomposition of the hydrogen peroxide as well as organic hydroperoxides by reduced glutathion and seems to be a member of the glutathion peroxidases family.</description><subject>28-kDa protein</subject><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Antibodies</subject><subject>Cattle</subject><subject>Chromatography, Gel</subject><subject>Electrophoresis, Polyacrylamide Gel</subject><subject>Epithelium - metabolism</subject><subject>Glutathione</subject><subject>Glutathione peroxidase</subject><subject>Glutathione Peroxidase - biosynthesis</subject><subject>Glutathione Peroxidase - chemistry</subject><subject>Glutathione Peroxidase - isolation & purification</subject><subject>Isoenzymes - biosynthesis</subject><subject>Isoenzymes - chemistry</subject><subject>Isoenzymes - isolation & purification</subject><subject>Methionine - metabolism</subject><subject>Molecular Sequence Data</subject><subject>Molecular Weight</subject><subject>Olfactory epithelium</subject><subject>Olfactory Mucosa - metabolism</subject><subject>Organ Specificity</subject><subject>Rabbits - immunology</subject><subject>Rat</subject><subject>Rats</subject><subject>Sequence Homology, Amino Acid</subject><subject>Sulfur Radioisotopes</subject><issn>0014-5793</issn><issn>1873-3468</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkNFLwzAQxoMoc07_A4U-iT5UkyZNExBB56bC0Bd9Dml6xWi7zKSd7L-33cYexafj7vvuu-OH0CnBVwQTfo0xYXGaSXoh-SXGOCMx3UNDIjIaU8bFPhruLIfoKITPzkQEkQM0EJwRRsQQ3by4JVRRIuKvBx0FMB4a51fRwrsG7Dwqvasjr5vIVaU2awkWtvmAyrb1MToodRXgZFtH6H06eRs_xbPXx-fx3Sw2jHMamzI1hCWGcq5pyqDIC9Ayw0KkOZEp5CyVjHHJSwGZ4QUYXGjKklISA6AxHaHzTW731XcLoVG1DQaqSs_BtUFlAuOUZKIzso3ReBeCh1ItvK21XymCVQ9N9URUT0TJvumgKdqtnW3z27yGYre0pdTp043-YytY_StTTSf3SS_0c8nX0_7Q7SYIOlpLC14FY2FuoLAeTKMKZ__-9BeOx432</recordid><startdate>19960226</startdate><enddate>19960226</enddate><creator>Peshenko, I.V.</creator><creator>Novoselov, V.I.</creator><creator>Evdokimov, V.A.</creator><creator>Nikolaev, Yu.V.</creator><creator>Shuvaeva, T.M.</creator><creator>Lipkin, V.M.</creator><creator>Fesenko, E.E.</creator><general>Elsevier B.V</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19960226</creationdate><title>Novel 28-kDa secretory protein from rat olfactory epithelium</title><author>Peshenko, I.V. ; Novoselov, V.I. ; Evdokimov, V.A. ; Nikolaev, Yu.V. ; Shuvaeva, T.M. ; Lipkin, V.M. ; Fesenko, E.E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4663-cf5c142c366a354edbdea970885b195eb45944696f8e7c6dec0da342f91ceea03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>28-kDa protein</topic><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Antibodies</topic><topic>Cattle</topic><topic>Chromatography, Gel</topic><topic>Electrophoresis, Polyacrylamide Gel</topic><topic>Epithelium - metabolism</topic><topic>Glutathione</topic><topic>Glutathione peroxidase</topic><topic>Glutathione Peroxidase - biosynthesis</topic><topic>Glutathione Peroxidase - chemistry</topic><topic>Glutathione Peroxidase - isolation & purification</topic><topic>Isoenzymes - biosynthesis</topic><topic>Isoenzymes - chemistry</topic><topic>Isoenzymes - isolation & purification</topic><topic>Methionine - metabolism</topic><topic>Molecular Sequence Data</topic><topic>Molecular Weight</topic><topic>Olfactory epithelium</topic><topic>Olfactory Mucosa - metabolism</topic><topic>Organ Specificity</topic><topic>Rabbits - immunology</topic><topic>Rat</topic><topic>Rats</topic><topic>Sequence Homology, Amino Acid</topic><topic>Sulfur Radioisotopes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Peshenko, I.V.</creatorcontrib><creatorcontrib>Novoselov, V.I.</creatorcontrib><creatorcontrib>Evdokimov, V.A.</creatorcontrib><creatorcontrib>Nikolaev, Yu.V.</creatorcontrib><creatorcontrib>Shuvaeva, T.M.</creatorcontrib><creatorcontrib>Lipkin, V.M.</creatorcontrib><creatorcontrib>Fesenko, E.E.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>FEBS letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Peshenko, I.V.</au><au>Novoselov, V.I.</au><au>Evdokimov, V.A.</au><au>Nikolaev, Yu.V.</au><au>Shuvaeva, T.M.</au><au>Lipkin, V.M.</au><au>Fesenko, E.E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel 28-kDa secretory protein from rat olfactory epithelium</atitle><jtitle>FEBS letters</jtitle><addtitle>FEBS Lett</addtitle><date>1996-02-26</date><risdate>1996</risdate><volume>381</volume><issue>1</issue><spage>12</spage><epage>14</epage><pages>12-14</pages><issn>0014-5793</issn><eissn>1873-3468</eissn><abstract>We have isolated a novel secretory 28-kDa protein which is an abundant component of the rat olfactory mucosa. The partial sequence of the 28-kDa protein has been determined. The amino acid sequence of the 28-kDa protein is similar to that of non-selenium glutathione peroxidase from bovine ciliary body. The 28-kDa protein catalyzed decomposition of the hydrogen peroxide as well as organic hydroperoxides by reduced glutathion and seems to be a member of the glutathion peroxidases family.</abstract><cop>England</cop><pub>Elsevier B.V</pub><pmid>8641418</pmid><doi>10.1016/0014-5793(96)00071-3</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | FEBS letters, 1996-02, Vol.381 (1), p.12-14 |
| issn | 0014-5793 1873-3468 |
| language | eng |
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| source | MEDLINE; Wiley Journals; Elsevier ScienceDirect Journals Complete; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | 28-kDa protein Amino Acid Sequence Animals Antibodies Cattle Chromatography, Gel Electrophoresis, Polyacrylamide Gel Epithelium - metabolism Glutathione Glutathione peroxidase Glutathione Peroxidase - biosynthesis Glutathione Peroxidase - chemistry Glutathione Peroxidase - isolation & purification Isoenzymes - biosynthesis Isoenzymes - chemistry Isoenzymes - isolation & purification Methionine - metabolism Molecular Sequence Data Molecular Weight Olfactory epithelium Olfactory Mucosa - metabolism Organ Specificity Rabbits - immunology Rat Rats Sequence Homology, Amino Acid Sulfur Radioisotopes |
| title | Novel 28-kDa secretory protein from rat olfactory epithelium |
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