PRENATAL DIAGNOSIS OF INTRACRANIAL LIPOMA ASSOCIATED WITH AGENESIS OF THE CORPUS CALLOSUM

BACKGROUNDLipoma of the corpus callosum is a congenital malformation present in 1:1700 individuals. Only three cases of prenatal sonographic diagnosis have been described. CASESTwo caes of prenatal sonographic diagnosis of jintracranial lipoma are described. The first case was visible at 26 weeksʼ gestation and was associated with partial agenesis of the corpus callosum, a characteristic midline gyral pattern, and fetal colpocephaly. The second case was an isolated lipoma diagnosed at 37 weeks. In both cases transvaginal scanning and color Doppler studies were useful adjuncts in making the diagnosis. CONCLUSIONPrenatal songographic diagnosis of intracranial lipoma associated with agenesis of the corpus callosum is possible as earily as 26 weeksʼ gestation. Because prognosis depends on associated anomalies, a detailed examination of fetal intracranial anatomy and a complete anatomic survey should be performed. Awareness of this lesion can be expected to increse its detection on prenatal sonogrphy.