Kalimantacins A, B and C, Novel Antibiotics from Alcaligenes sp. YL-02632S: I. Taxonomy, Fermentation, Isolation and Biological Properties

Novel antibacterial antibiotics, kalimantacins A, B and C, have been isolated from the fermentation broth of Alcaligenes sp. YL-02632S. In this paper, the taxonomy of the producing strain, fermentation, isolation and biological activities of kalimantacins are reported. Kalimantacins inhibit the grow...

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Veröffentlicht in:	Journal of antibiotics 1996/02/25, Vol.49(2), pp.136-139
Hauptverfasser:	KAMIGIRI, KAZUMA, SUZUKI, YASUTO, SHIBAZAKI, MITSUYOSHI, MORIOKA, MOTOO, SUZUKI, KEN-ICHI, TOKUNAGA, TATSUHIRO, SETIAWAN, BOENJAMIN, RANTIATMODJO, RATNA MURNI
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcaligenes Alcaligenes - classification Alcaligenes - metabolism Animals Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antibiotics (antibacterial agents, antifungal agents) Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents Applied microbiology Biological and medical sciences Carbamates - chemistry Carbamates - isolation & purification Carbamates - pharmacology Fatty Acids, Unsaturated - chemistry Fatty Acids, Unsaturated - isolation & purification Fatty Acids, Unsaturated - pharmacology Fundamental and applied biological sciences. Psychology HeLa Cells Humans Leukemia P388 - pathology Mice Microbiology Molecular Structure Staphylococcus aureus - drug effects Staphylococcus epidermidis - drug effects
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Zusammenfassung:	Novel antibacterial antibiotics, kalimantacins A, B and C, have been isolated from the fermentation broth of Alcaligenes sp. YL-02632S. In this paper, the taxonomy of the producing strain, fermentation, isolation and biological activities of kalimantacins are reported. Kalimantacins inhibit the growth of Staphylococcus aureus and S. epidermidis including multiple-drug resistant strains.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.49.136