Growth factor production after polytetrafluoroethylene and vein arterial grafting: an experimental study

Purpose: Occlusion caused by myointimal hyperplasia appears to be the main reason of late failure of polytetrafluoroethylene (PTFE) arterial bypass grafts. Evidence exists that growth factors are involved in the genesis of myointimal hyperplasia. The aim of this study was to assess the release of pl...

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Veröffentlicht in:Journal of vascular surgery 1996-03, Vol.23 (3), p.453-460
Hauptverfasser: Sterpetti, Antonio V., Lepidi, Sandro, Cucina, Alessandra, Patrizi, Anna L., Palumbo, Roberta, Taranta, Anna, Stipa, Francesco, Cavallaro, Antonino, Santoro-D'Angelo, Luciana, Stipa, Sergio
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container_end_page 460
container_issue 3
container_start_page 453
container_title Journal of vascular surgery
container_volume 23
creator Sterpetti, Antonio V.
Lepidi, Sandro
Cucina, Alessandra
Patrizi, Anna L.
Palumbo, Roberta
Taranta, Anna
Stipa, Francesco
Cavallaro, Antonino
Santoro-D'Angelo, Luciana
Stipa, Sergio
description Purpose: Occlusion caused by myointimal hyperplasia appears to be the main reason of late failure of polytetrafluoroethylene (PTFE) arterial bypass grafts. Evidence exists that growth factors are involved in the genesis of myointimal hyperplasia. The aim of this study was to assess the release of platelet-derived growth factor (PDGF) and basic fibroblastic growth factor (bFGF) by PTFE arterial grafts. Methods: Results: Conclusions:
doi_str_mv 10.1016/S0741-5214(96)80010-3
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Graft diseases</subject><subject>Tunica Intima - pathology</subject><subject>Vascular surgery: aorta, extremities, vena cava. 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subjects Anastomosis, Surgical
Animals
Aorta, Abdominal - pathology
Aorta, Abdominal - surgery
Biological and medical sciences
Blood Vessel Prosthesis
Graft Occlusion, Vascular
Growth Substances - analysis
Growth Substances - biosynthesis
Hyperplasia - etiology
Hyperplasia - pathology
Male
Medical sciences
Polytetrafluoroethylene
Rats
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Tunica Intima - pathology
Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels
Vena Cava, Inferior - pathology
Vena Cava, Inferior - transplantation
title Growth factor production after polytetrafluoroethylene and vein arterial grafting: an experimental study
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