Extending the recognition site of designed minor groove binding molecules
A linked, imazole/pyrrole minor-groove ligand has been shown to bind sequence specif icially to a 13 base-pair target sequence in a mixed 1:1/2:1 mode.
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| Veröffentlicht in: | Nature Structural Biology 1996-04, Vol.3 (4), p.321-324 |
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| container_end_page | 324 |
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| container_issue | 4 |
| container_start_page | 321 |
| container_title | Nature Structural Biology |
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| creator | Geierstanger, Bernhard H Mrksich, Milan Dervan, Peter B Wemmer, David E |
| description | A linked, imazole/pyrrole minor-groove ligand has been shown to bind sequence specif icially to a 13 base-pair target sequence in a mixed 1:1/2:1 mode. |
| doi_str_mv | 10.1038/nsb0496-321 |
| format | Article |
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| ispartof | Nature Structural Biology, 1996-04, Vol.3 (4), p.321-324 |
| issn | 1072-8368 1545-9993 2331-365X 1545-9985 |
| language | eng |
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| source | MEDLINE; Nature; SpringerNature Journals |
| subjects | Base Sequence Binding Sites Biochemistry Biological Microscopy Biomedical and Life Sciences correspondence DNA - chemistry DNA - metabolism Life Sciences Ligands Membrane Biology Models, Molecular Molecular Sequence Data Oligodeoxyribonucleotides - metabolism Protein Structure Pyrroles - chemistry Pyrroles - metabolism |
| title | Extending the recognition site of designed minor groove binding molecules |
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