Case report: successful treatment with cimetidine and zinc sulphate in chronic mucocutaneous candidiasis

The authors evaluated the clinical efficacy of a treatment with cimetidine and zinc sulphate in a patient with chronic mucocutaneous candidiasis. Cimetidine was given at a dose of 400 mg three times daily; zinc sulphate at a dose of 200 mg daily, then adjusted to maintain blood zinc levels at the up...

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Veröffentlicht in:	The American journal of the medical sciences 1996-04, Vol.311 (4), p.189-190
Hauptverfasser:	Polizzi, B, Origgi, L, Zuccaro, G, Matti, P, Scorza, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - therapeutic use Adult AIDS/HIV Candidiasis, Chronic Mucocutaneous - blood Candidiasis, Chronic Mucocutaneous - drug therapy CD4 Lymphocyte Count - drug effects Cimetidine - therapeutic use Female Humans Sulfates - therapeutic use Zinc Compounds - therapeutic use Zinc Sulfate
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Zusammenfassung:	The authors evaluated the clinical efficacy of a treatment with cimetidine and zinc sulphate in a patient with chronic mucocutaneous candidiasis. Cimetidine was given at a dose of 400 mg three times daily; zinc sulphate at a dose of 200 mg daily, then adjusted to maintain blood zinc levels at the upper normal range. This treatment lasted 16 months. An impressive and significant reduction of the infectious events and an increased CD4 (helper/inducer) cell counts were observed. The authors conclude that this combined immunopotentiating treatment is safe and inexpensive to treat immunodeficiency disorders.
ISSN:	0002-9629
DOI:	10.1016/s0002-9629(15)41682-9