Is a baseline electrophysiologic study mandatory for the management of patients with spontaneous, sustained, ventricular tachyarrhythmias?

Should the patient being treated for spontaneous, sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) routinely undergo a baseline, diagnostic, catheter electrophysiologic (EP) study? The potential patient advantages of such a policy include identification of the tachyarrhythmia-initiating episodes of presumed VT or VF, prediction of the subsequent risk of VT/VF recurrences, identification of VT mechanisms amenable to cure by catheter ablation, assessment of the response of a patient's VT to attempts at pace termination, evaluation of the patient's candidacy for some of the approaches to VT/VF therapy selection, and enhancement of our understanding of the mechanisms and therapeutics of VT/VF. Disadvantages of such a policy include patient discomfort, patient risks, and cost. Recognizing that the decision to perform a baseline catheter EP study in a patient with VT/VF must be based on an individualized, patient-based, risk-benefit analysis; this review details each of the advantages and disadvantages of doing so to identify patient populations for whom a baseline catheter EP study is or is not usually indicated.