Pregnancy induced hypertension: changes in coagulation profile of newborns

Coagulation parameters and platelet count were studied in 30 neonates of mothers with pregnancy induced hypertension (PIH). 30 neonates born to normotensive mothers were taken as controls. The test group was further subdivided as neonates born to mothers with gestational hypertension, pre-eclamptic...

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Veröffentlicht in:	Indian journal of pathology & microbiology 1995-07, Vol.38 (3), p.281-285
Hauptverfasser:	Agarwal, K, Narayan, S, Kumari, S, Logani, K B, Agarwal, A K
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Coagulation Disorders - blood Blood Coagulation Disorders - congenital Blood Coagulation Factors - metabolism Eclampsia - complications Female Humans Hypertension - complications Infant, Newborn Male Pre-Eclampsia - complications Pregnancy Pregnancy Complications, Cardiovascular Thrombocytopenia - blood Thrombocytopenia - congenital
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Zusammenfassung:	Coagulation parameters and platelet count were studied in 30 neonates of mothers with pregnancy induced hypertension (PIH). 30 neonates born to normotensive mothers were taken as controls. The test group was further subdivided as neonates born to mothers with gestational hypertension, pre-eclamptic toxemia and eclampsia. The values of Prothrombin Time, Partial Thromboplastin Time with Kaolin, Thrombin Time, Fibrinogen Degradation Products were significantly raised and Fibrinogen and Platelet count were reduced significantly in both term and preterm test groups as compared to controls. The derangement in coagulation parameters was more marked with increasing severity of PIH.
ISSN:	0377-4929