Demonstration of human papillomavirus types 6 and 11 in juvenile laryngeal papillomatosis by in-situ DNA hybridization

A study is reported in which an in situ hybridization technique for the demonstration of human papillomavirus (HPV) employing a biotin–streptavidin polyalkaline phosphatase complex has been successfully applied to formalin‐fixed paraffin‐processed tissue obtained from ten patients with juvenile lary...

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Veröffentlicht in:The Journal of pathology 1987-11, Vol.153 (3), p.245-248
Hauptverfasser: Terry, R. M., Lewis, F. A., Griffiths, S., Wells, M., Bird, C. C.
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container_end_page 248
container_issue 3
container_start_page 245
container_title The Journal of pathology
container_volume 153
creator Terry, R. M.
Lewis, F. A.
Griffiths, S.
Wells, M.
Bird, C. C.
description A study is reported in which an in situ hybridization technique for the demonstration of human papillomavirus (HPV) employing a biotin–streptavidin polyalkaline phosphatase complex has been successfully applied to formalin‐fixed paraffin‐processed tissue obtained from ten patients with juvenile laryngeal papillomatosis. In all cases, positive results were obtained for either HPV type 6 or 11. Normal vocal cord epithelium was negative.
doi_str_mv 10.1002/path.1711530308
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Biological and medical sciences
DNA hybridization
DNA, Viral - analysis
Human papillomaviruses
Human viral diseases
Humans
Infectious diseases
juvenile laryngeal papillomatosis
Laryngeal Neoplasms - microbiology
Medical sciences
Microbiological Techniques
Nucleic Acid Hybridization
Papilloma - microbiology
Papillomaviridae - isolation & purification
Viral diseases
Viral diseases of the respiratory system and ent viral diseases
title Demonstration of human papillomavirus types 6 and 11 in juvenile laryngeal papillomatosis by in-situ DNA hybridization
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