Subunits of Yeast RNA Polymerase II Transcription Factor TFIIH Encoded by the CCL1 Gene (∗)

Both 45- and 47-kDa subunits of TFIIK, a subcomplex of RNA polymerase II general transcription factor TFIIH, are encoded by the yeast cyclin gene CCL1. In all likelihood, these two subunits individually form cyclin-dependent kinase/cyclin dimers with Kin28 protein, a key enzyme in phosphorylation of...

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Veröffentlicht in:	The Journal of biological chemistry 1996-01, Vol.271 (2), p.643-645
Hauptverfasser:	Svejstrup, Jesper Q., Feaver, William J., Kornberg, Roger D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence GENE GENES Genes, Fungal Molecular Sequence Data RNA Polymerase II - metabolism SACCHAROMYCES CEREVISIAE Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins TATA-Binding Protein Associated Factors Transcription Factor TFIID Transcription Factor TFIIH Transcription Factors - genetics Transcription Factors - metabolism Transcription Factors, TFII TRANSFERASAS TRANSFERASE
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Beschreibung
Zusammenfassung:	Both 45- and 47-kDa subunits of TFIIK, a subcomplex of RNA polymerase II general transcription factor TFIIH, are encoded by the yeast cyclin gene CCL1. In all likelihood, these two subunits individually form cyclin-dependent kinase/cyclin dimers with Kin28 protein, a key enzyme in phosphorylation of the C-terminal domain of RNA polymerase II concomitant with transcription.
ISSN:	0021-9258 1083-351X
DOI:	10.1074/jbc.271.2.643