Chemical Constituents of Halophilic Facultatively Anaerobic Bacteria, 1

Two new nitrotyramine derivatives, 1 and 2, along with five known aromatic compounds, were isolated from the culture broth of a facultatively anaerobic, halophilic bacterium isolated from a sediment from the Great Salt Plains, Alfalfa County, Oklahoma. The structures of the new compounds were determ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1995-12, Vol.58 (12), p.1950-1954
Hauptverfasser:	Fu, Xiong, Schmitz, Francis J, Tanner, Ralph S
Format:	Artikel
Sprache:	eng
Schlagworte:	AMINAS AMINE AMINES ANAEROBES ANAEROBIOSE ANAEROBIOSIS Animals Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Applied microbiology AROMATIC COMPOUNDS BACTERIA Bacteria, Anaerobic - chemistry Biological and medical sciences CELL CULTURE CELL LINES CHEMICAL COMPOSITION Chemotherapic agents COMPOSE AROMATIQUE COMPOSICION QUIMICA COMPOSITION CHIMIQUE COMPUESTOS AROMATICOS CULTIVO DE CELULAS CULTURE DE CELLULE CYTOTOXIC COMPOUNDS DERIVATIVES ESPECTROMETRIA FILTRACION FILTRATION FLORA DEL SUELO FLORE DU SOL Fundamental and applied biological sciences. Psychology LEUCEMIA LEUCEMIE LEUKAEMIA Leukemia P388 - drug therapy Magnetic Resonance Spectroscopy Mice Microbiology MICROORGANISME MICROORGANISMOS MICROORGANISMS MOLECULAR CONFORMATION molecular structure murine leukemia p-388 cell line OKLAHOMA SALT TOLERANCE SEDIMENT SEDIMENTO SOIL FLORA Soil Microbiology SPECTRAL ANALYSIS SPECTROMETRIE SPECTROMETRY SUBSTANCE TOXIQUE SUSTANCIAS TOXICAS TOLERANCE AU SEL TOLERANCIA A LA SAL TOXIC SUBSTANCES TYRAMINE Tyramine - analogs & derivatives Tyramine - chemistry Tyramine - isolation & purification Tyramine - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Two new nitrotyramine derivatives, 1 and 2, along with five known aromatic compounds, were isolated from the culture broth of a facultatively anaerobic, halophilic bacterium isolated from a sediment from the Great Salt Plains, Alfalfa County, Oklahoma. The structures of the new compounds were determined from spectral data and were confirmed by synthesis from tyramine hydrochloride. Compound 1 showed cytotoxicity against the murine leukemia P-388 cell line (IC50 3 micrograms/ml).
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np50126a026