Effects of external radiotherapy on uterine blood flow in patients with advanced cervical carcinoma assessed by Color Doppler ultrasonography

Background. This study was designed to evaluate radiation‐induced changes in tumor blood flow by color Doppler ultrasonogr. Methods. Color Doppler examination was performed on 14 patients with advanced cervical carcinoma treated with external radiotherapy. The total dose of radiation varied from 30...

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Veröffentlicht in:Cancer 1995-07, Vol.76 (1), p.67-71
Hauptverfasser: Pirhonen, Jouko P., Grenman, Seija A., Bredbacka, Åse B., Bahado‐Singh, Ray O., Salmi, Tuula A.
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Sprache:eng
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Zusammenfassung:Background. This study was designed to evaluate radiation‐induced changes in tumor blood flow by color Doppler ultrasonogr. Methods. Color Doppler examination was performed on 14 patients with advanced cervical carcinoma treated with external radiotherapy. The total dose of radiation varied from 30 to 65 Gy and was given as 1.9 Gy daily fractions, 5 days/week. Tumor vascularity and blood flow impedance were measured by one pretreatment and five follow‐up examinations. Results. At the baseline examination, 11 of 14 patients had very low tumor blood flow impedance (
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19950701)76:1<67::AID-CNCR2820760109>3.0.CO;2-0