PAUCIBACILLARY LEPROSY PATIENTS TREATED WITH MULTIDRUG THERAPY FOUR YEARS EXPERIENCE (1988 to 1991) IN BANGLADESH

Two hundred and fifty paucibacillary (PB) leprosy patients were treated with WHO recommended multidrug therapy (MDT) and followed up them for four years. The paucibacillary MDT regimen (PBR) was well accepted and tolerated by the patients. Clinical regression was attained in 60% patients after 6 dos...

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Veröffentlicht in:	Japanese journal of leprosy 1994/11/30, Vol.63(3), pp.95-98
Hauptverfasser:	Faruque, Eshaq, A K M Anisul Hoque, Ahmed, Jalaluddin, Ahmed, Rukunuddin, Md, A K, Ali, Ahsan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bangladesh Biological and medical sciences Child Dapsone - administration & dosage Drug Therapy, Combination - administration & dosage Female Follow-Up Studies Humans leprosy Leprosy - drug therapy Male MDT Medical sciences Middle Aged paucibacillary Pharmacology. Drug treatments Rifampin - administration & dosage Tropical medicine
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Beschreibung
Zusammenfassung:	Two hundred and fifty paucibacillary (PB) leprosy patients were treated with WHO recommended multidrug therapy (MDT) and followed up them for four years. The paucibacillary MDT regimen (PBR) was well accepted and tolerated by the patients. Clinical regression was attained in 60% patients after 6 doses of PBR. Reversal reaction occurred in 14% cases and relapse were found in 1.6% cases 18-24 months after completing the treatment. The incidence of reversal reaction was high in patients with more than 2 thickened nerve trunks associated with more than 5 patches.
ISSN:	0386-3980 2185-1360
DOI:	10.5025/hansen1977.63.95