Post‐transplant lymphoma in a liver allograft

We describe the development of a lymphoma in a liver allograft shortly after orthotopic liver transplantation. Aspiration and core biopsies of the nodule were persistently negative so that a diagnosis could not be made until the patient underwent retransplantation, when examination of the liver rese...

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Veröffentlicht in:	Transplant international 1995-11, Vol.8 (6), p.488-491
Hauptverfasser:	Ribas, Y., Rafecas, A., Figueras, J., Benasco, C., Fabregat, J., Torras, J., Cañas, C., Valls, C., Volpini, V., Banchs, I., Jaurrieta, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences B‐cell lymphoma DNA, Neoplasm - analysis Humans Liver Neoplasms - diagnosis Liver Neoplasms - etiology Liver transplantation Liver Transplantation - adverse effects Liver, biliary tract, pancreas, portal circulation, spleen Lymphoma, B-Cell - diagnosis Lymphoma, B-Cell - etiology Male Medical sciences Middle Aged Molecular Sequence Data Polymerase Chain Reaction Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system Transplantation, Homologous
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Beschreibung
Zusammenfassung:	We describe the development of a lymphoma in a liver allograft shortly after orthotopic liver transplantation. Aspiration and core biopsies of the nodule were persistently negative so that a diagnosis could not be made until the patient underwent retransplantation, when examination of the liver resection specimen revealed a B‐cell lymphoma. Using a rapid technique based on the polymerase chain reaction, we were able to demonstrate that the tumor was of donor origin.
ISSN:	0934-0874 1432-2277
DOI:	10.1111/j.1432-2277.1995.tb01561.x