Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area
The comparative efficacy of albendazole and mebendazole in the treatment of intestinal nematode infections were compared 3 weeks after treatment in a randomized trial among schoolchildren on Pemba Island, Tanzania. Egg counts were compared 3 weeks, 4 months and 6 months after treatment of 731 childr...
Gespeichert in:
| Veröffentlicht in: | Transactions of the Royal Society of Tropical Medicine and Hygiene 1995-09, Vol.89 (5), p.538-541 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 541 |
|---|---|
| container_issue | 5 |
| container_start_page | 538 |
| container_title | Transactions of the Royal Society of Tropical Medicine and Hygiene |
| container_volume | 89 |
| creator | Albonico, Marco Smith, Peter G. Ercole, Elena Hall, Andrew Chwaya, Hababu M. Alawi, Kassim S. Savioli, Lorenzo |
| description | The comparative efficacy of albendazole and mebendazole in the treatment of intestinal nematode infections were compared 3 weeks after treatment in a randomized trial among schoolchildren on Pemba Island, Tanzania. Egg counts were compared 3 weeks, 4 months and 6 months after treatment of 731 children seen on each occasion. Differences in the efficacies were apparent with some nematodes 21 d after treatment, but these were no longer apparent 4 months after treatment, and by 6 months intensities of infection were similar to pre-treatment levels. These findings suggest that treatment of schoolchildren every 4 months may be necessary in this highly endemic area in order to have an impact on the intensity of intestinal nematode infections sufficient to be likely to reduce morbidity. |
| doi_str_mv | 10.1016/0035-9203(95)90101-9 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_77792905</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0035920395901019</els_id><sourcerecordid>77792905</sourcerecordid><originalsourceid>FETCH-LOGICAL-c424t-528110709a308ae663a4b821f7a936eedf04caf65c41a4e880e24f3d57742afa3</originalsourceid><addsrcrecordid>eNp9kUGLFDEQhYMo6-zoP1DIQWQ9tCadTndyEWRxHGFEEIVlL6EmXXGi3endJKOuR3-5aWYYb56K1PveI3kh5AlnLznj7SvGhKx0zcSFli80K7tK3yMLrjpVCcnEfbI4IQ_JeUrfGKsll_qMnCnZMinkgvz5BBnp5GhEHxza7KdAf_q8oz5kTNkHGGjAEfLUY6LgMkaaI0IeMeTZaHd-6CMeXSNuMfTwexpKaqQw_Dv6QIHu_NfdcEfLEkdvKZSkR-SBgyHh4-Ncki-rt58v19Xm47v3l282lW3qJleyVpyzjmkQTAG2rYBmq2ruOtCiRewdayy4VtqGQ4NKMawbJ3rZdU0NDsSSPD_k3sTpdl_eZkafLA4DBJz2yXRdp2tdalmS5gDaOKUU0Zmb6EeId4YzM1dv5l7N3KvRZc7VG11sT4_5--2I_cl07Lroz446JAuDixCsTyes1rwVShSsOmA-Zfx1kiF-N20nOmnWV9dms7q6Vh_42qwK__rAY-nuh8dokvUYLPY-lv80_eT_f--_G1OwfQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>77792905</pqid></control><display><type>article</type><title>Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Albonico, Marco ; Smith, Peter G. ; Ercole, Elena ; Hall, Andrew ; Chwaya, Hababu M. ; Alawi, Kassim S. ; Savioli, Lorenzo</creator><creatorcontrib>Albonico, Marco ; Smith, Peter G. ; Ercole, Elena ; Hall, Andrew ; Chwaya, Hababu M. ; Alawi, Kassim S. ; Savioli, Lorenzo</creatorcontrib><description>The comparative efficacy of albendazole and mebendazole in the treatment of intestinal nematode infections were compared 3 weeks after treatment in a randomized trial among schoolchildren on Pemba Island, Tanzania. Egg counts were compared 3 weeks, 4 months and 6 months after treatment of 731 children seen on each occasion. Differences in the efficacies were apparent with some nematodes 21 d after treatment, but these were no longer apparent 4 months after treatment, and by 6 months intensities of infection were similar to pre-treatment levels. These findings suggest that treatment of schoolchildren every 4 months may be necessary in this highly endemic area in order to have an impact on the intensity of intestinal nematode infections sufficient to be likely to reduce morbidity.</description><identifier>ISSN: 0035-9203</identifier><identifier>EISSN: 1878-3503</identifier><identifier>DOI: 10.1016/0035-9203(95)90101-9</identifier><identifier>PMID: 8560535</identifier><identifier>CODEN: TRSTAZ</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>albendazole ; Albendazole - therapeutic use ; Antinematodal Agents - therapeutic use ; Ascariasis ; Ascariasis - drug therapy ; Ascaris ; Biological and medical sciences ; chemotherapy ; Child ; Diseases caused by nematodes ; Feces - parasitology ; Helminthic diseases ; hookworm ; Hookworm Infections - drug therapy ; Humans ; Infectious diseases ; Intestinal Diseases, Parasitic - drug therapy ; mebendazole ; Mebendazole - therapeutic use ; Medical sciences ; Parasite Egg Count ; Parasitic diseases ; Pemba Island ; Recurrence ; Sampling Studies ; Tanzania ; Time Factors ; Treatment Outcome ; Trichuriasis - drug therapy ; Trichuris ; Tropical medicine</subject><ispartof>Transactions of the Royal Society of Tropical Medicine and Hygiene, 1995-09, Vol.89 (5), p.538-541</ispartof><rights>1995</rights><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c424t-528110709a308ae663a4b821f7a936eedf04caf65c41a4e880e24f3d57742afa3</citedby><cites>FETCH-LOGICAL-c424t-528110709a308ae663a4b821f7a936eedf04caf65c41a4e880e24f3d57742afa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2916383$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8560535$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Albonico, Marco</creatorcontrib><creatorcontrib>Smith, Peter G.</creatorcontrib><creatorcontrib>Ercole, Elena</creatorcontrib><creatorcontrib>Hall, Andrew</creatorcontrib><creatorcontrib>Chwaya, Hababu M.</creatorcontrib><creatorcontrib>Alawi, Kassim S.</creatorcontrib><creatorcontrib>Savioli, Lorenzo</creatorcontrib><title>Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area</title><title>Transactions of the Royal Society of Tropical Medicine and Hygiene</title><addtitle>Trans R Soc Trop Med Hyg</addtitle><description>The comparative efficacy of albendazole and mebendazole in the treatment of intestinal nematode infections were compared 3 weeks after treatment in a randomized trial among schoolchildren on Pemba Island, Tanzania. Egg counts were compared 3 weeks, 4 months and 6 months after treatment of 731 children seen on each occasion. Differences in the efficacies were apparent with some nematodes 21 d after treatment, but these were no longer apparent 4 months after treatment, and by 6 months intensities of infection were similar to pre-treatment levels. These findings suggest that treatment of schoolchildren every 4 months may be necessary in this highly endemic area in order to have an impact on the intensity of intestinal nematode infections sufficient to be likely to reduce morbidity.</description><subject>albendazole</subject><subject>Albendazole - therapeutic use</subject><subject>Antinematodal Agents - therapeutic use</subject><subject>Ascariasis</subject><subject>Ascariasis - drug therapy</subject><subject>Ascaris</subject><subject>Biological and medical sciences</subject><subject>chemotherapy</subject><subject>Child</subject><subject>Diseases caused by nematodes</subject><subject>Feces - parasitology</subject><subject>Helminthic diseases</subject><subject>hookworm</subject><subject>Hookworm Infections - drug therapy</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Intestinal Diseases, Parasitic - drug therapy</subject><subject>mebendazole</subject><subject>Mebendazole - therapeutic use</subject><subject>Medical sciences</subject><subject>Parasite Egg Count</subject><subject>Parasitic diseases</subject><subject>Pemba Island</subject><subject>Recurrence</subject><subject>Sampling Studies</subject><subject>Tanzania</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Trichuriasis - drug therapy</subject><subject>Trichuris</subject><subject>Tropical medicine</subject><issn>0035-9203</issn><issn>1878-3503</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUGLFDEQhYMo6-zoP1DIQWQ9tCadTndyEWRxHGFEEIVlL6EmXXGi3endJKOuR3-5aWYYb56K1PveI3kh5AlnLznj7SvGhKx0zcSFli80K7tK3yMLrjpVCcnEfbI4IQ_JeUrfGKsll_qMnCnZMinkgvz5BBnp5GhEHxza7KdAf_q8oz5kTNkHGGjAEfLUY6LgMkaaI0IeMeTZaHd-6CMeXSNuMfTwexpKaqQw_Dv6QIHu_NfdcEfLEkdvKZSkR-SBgyHh4-Ncki-rt58v19Xm47v3l282lW3qJleyVpyzjmkQTAG2rYBmq2ruOtCiRewdayy4VtqGQ4NKMawbJ3rZdU0NDsSSPD_k3sTpdl_eZkafLA4DBJz2yXRdp2tdalmS5gDaOKUU0Zmb6EeId4YzM1dv5l7N3KvRZc7VG11sT4_5--2I_cl07Lroz446JAuDixCsTyes1rwVShSsOmA-Zfx1kiF-N20nOmnWV9dms7q6Vh_42qwK__rAY-nuh8dokvUYLPY-lv80_eT_f--_G1OwfQ</recordid><startdate>19950901</startdate><enddate>19950901</enddate><creator>Albonico, Marco</creator><creator>Smith, Peter G.</creator><creator>Ercole, Elena</creator><creator>Hall, Andrew</creator><creator>Chwaya, Hababu M.</creator><creator>Alawi, Kassim S.</creator><creator>Savioli, Lorenzo</creator><general>Elsevier Ltd</general><general>Royal Society of Tropical Medicine and Hygiene</general><general>Elsevier</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19950901</creationdate><title>Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area</title><author>Albonico, Marco ; Smith, Peter G. ; Ercole, Elena ; Hall, Andrew ; Chwaya, Hababu M. ; Alawi, Kassim S. ; Savioli, Lorenzo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c424t-528110709a308ae663a4b821f7a936eedf04caf65c41a4e880e24f3d57742afa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>albendazole</topic><topic>Albendazole - therapeutic use</topic><topic>Antinematodal Agents - therapeutic use</topic><topic>Ascariasis</topic><topic>Ascariasis - drug therapy</topic><topic>Ascaris</topic><topic>Biological and medical sciences</topic><topic>chemotherapy</topic><topic>Child</topic><topic>Diseases caused by nematodes</topic><topic>Feces - parasitology</topic><topic>Helminthic diseases</topic><topic>hookworm</topic><topic>Hookworm Infections - drug therapy</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Intestinal Diseases, Parasitic - drug therapy</topic><topic>mebendazole</topic><topic>Mebendazole - therapeutic use</topic><topic>Medical sciences</topic><topic>Parasite Egg Count</topic><topic>Parasitic diseases</topic><topic>Pemba Island</topic><topic>Recurrence</topic><topic>Sampling Studies</topic><topic>Tanzania</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Trichuriasis - drug therapy</topic><topic>Trichuris</topic><topic>Tropical medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Albonico, Marco</creatorcontrib><creatorcontrib>Smith, Peter G.</creatorcontrib><creatorcontrib>Ercole, Elena</creatorcontrib><creatorcontrib>Hall, Andrew</creatorcontrib><creatorcontrib>Chwaya, Hababu M.</creatorcontrib><creatorcontrib>Alawi, Kassim S.</creatorcontrib><creatorcontrib>Savioli, Lorenzo</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Transactions of the Royal Society of Tropical Medicine and Hygiene</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Albonico, Marco</au><au>Smith, Peter G.</au><au>Ercole, Elena</au><au>Hall, Andrew</au><au>Chwaya, Hababu M.</au><au>Alawi, Kassim S.</au><au>Savioli, Lorenzo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area</atitle><jtitle>Transactions of the Royal Society of Tropical Medicine and Hygiene</jtitle><addtitle>Trans R Soc Trop Med Hyg</addtitle><date>1995-09-01</date><risdate>1995</risdate><volume>89</volume><issue>5</issue><spage>538</spage><epage>541</epage><pages>538-541</pages><issn>0035-9203</issn><eissn>1878-3503</eissn><coden>TRSTAZ</coden><abstract>The comparative efficacy of albendazole and mebendazole in the treatment of intestinal nematode infections were compared 3 weeks after treatment in a randomized trial among schoolchildren on Pemba Island, Tanzania. Egg counts were compared 3 weeks, 4 months and 6 months after treatment of 731 children seen on each occasion. Differences in the efficacies were apparent with some nematodes 21 d after treatment, but these were no longer apparent 4 months after treatment, and by 6 months intensities of infection were similar to pre-treatment levels. These findings suggest that treatment of schoolchildren every 4 months may be necessary in this highly endemic area in order to have an impact on the intensity of intestinal nematode infections sufficient to be likely to reduce morbidity.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>8560535</pmid><doi>10.1016/0035-9203(95)90101-9</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0035-9203 |
| ispartof | Transactions of the Royal Society of Tropical Medicine and Hygiene, 1995-09, Vol.89 (5), p.538-541 |
| issn | 0035-9203 1878-3503 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77792905 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | albendazole Albendazole - therapeutic use Antinematodal Agents - therapeutic use Ascariasis Ascariasis - drug therapy Ascaris Biological and medical sciences chemotherapy Child Diseases caused by nematodes Feces - parasitology Helminthic diseases hookworm Hookworm Infections - drug therapy Humans Infectious diseases Intestinal Diseases, Parasitic - drug therapy mebendazole Mebendazole - therapeutic use Medical sciences Parasite Egg Count Parasitic diseases Pemba Island Recurrence Sampling Studies Tanzania Time Factors Treatment Outcome Trichuriasis - drug therapy Trichuris Tropical medicine |
| title | Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T20%3A05%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Rate%20of%20reinfection%20with%20intestinal%20nematodes%20after%20treatment%20of%20children%20with%20mebendazole%20or%20albendazole%20in%20a%20highly%20endemic%20area&rft.jtitle=Transactions%20of%20the%20Royal%20Society%20of%20Tropical%20Medicine%20and%20Hygiene&rft.au=Albonico,%20Marco&rft.date=1995-09-01&rft.volume=89&rft.issue=5&rft.spage=538&rft.epage=541&rft.pages=538-541&rft.issn=0035-9203&rft.eissn=1878-3503&rft.coden=TRSTAZ&rft_id=info:doi/10.1016/0035-9203(95)90101-9&rft_dat=%3Cproquest_cross%3E77792905%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=77792905&rft_id=info:pmid/8560535&rft_els_id=0035920395901019&rfr_iscdi=true |