Onset of Pro-Thyrotropin-Releasing Hormone Gene Expression in Cultured Rat Anterior Pituitary Cells Is Expedited by Dexamethasone

The early onset of proTRH gene expression in anterior pituitary (AP) cells in culture and its regulation by dexamethasone (DEX) were investigated. AP cells derived from 15-day-old rats were cultured for up to 4 days in the presence or absence of 10-7M DEX. TRH peptide levels, which could be detected...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular and cellular neuroscience 1994-12, Vol.5 (6), p.678-683
Hauptverfasser:	Rondeel, Jan M.M., Bruhn, Thomas O., Bolduc, Thomas G., Jackson, Ivor M.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Dexamethasone - pharmacology Gene Expression - drug effects In Situ Hybridization Male Pituitary Gland, Anterior - cytology Pituitary Gland, Anterior - physiology Protein Precursors - genetics Pyrrolidonecarboxylic Acid - analogs & derivatives Rats Thyrotropin-Releasing Hormone - genetics Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!