The ends and the middle: putting chromosomes together
The three known classes of eukaryotic telomeres share the requirement for an RNA template in their replication. This RNA-templated replication is subject to species-specific differences, such as telomere length and its regulation, which suggest that telomeres may have acquired different additional f...
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Veröffentlicht in: | Current opinion in genetics & development 1994-12, Vol.4 (6), p.845-850 |
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description | The three known classes of eukaryotic telomeres share the requirement for an RNA template in their replication. This RNA-templated replication is subject to species-specific differences, such as telomere length and its regulation, which suggest that telomeres may have acquired different additional functions in different organisms. Centromeres show less conservation than do telomeres. |
doi_str_mv | 10.1016/0959-437X(94)90069-8 |
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subjects | Animals Base Sequence Candida albicans Centromere - genetics Centromere - physiology Conserved Sequence DNA - genetics DNA Nucleotidylexotransferase - metabolism DNA Replication - physiology Drosophila melanogaster Humans Kluyveromyces Minisatellite Repeats Molecular Sequence Data Phylogeny Retroelements Telomere - genetics Telomere - physiology Templates, Genetic |
title | The ends and the middle: putting chromosomes together |
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