The ends and the middle: putting chromosomes together

The ends and the middle: putting chromosomes together

The three known classes of eukaryotic telomeres share the requirement for an RNA template in their replication. This RNA-templated replication is subject to species-specific differences, such as telomere length and its regulation, which suggest that telomeres may have acquired different additional f...

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Veröffentlicht in:Current opinion in genetics & development 1994-12, Vol.4 (6), p.845-850
1. Verfasser: Pardue, Mary Lou
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Base Sequence
Candida albicans
Centromere - genetics
Centromere - physiology
Conserved Sequence
DNA - genetics
DNA Nucleotidylexotransferase - metabolism
DNA Replication - physiology
Drosophila melanogaster
Humans
Kluyveromyces
Minisatellite Repeats
Molecular Sequence Data
Phylogeny
Retroelements
Telomere - genetics
Telomere - physiology
Templates, Genetic
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Beschreibung
Zusammenfassung:The three known classes of eukaryotic telomeres share the requirement for an RNA template in their replication. This RNA-templated replication is subject to species-specific differences, such as telomere length and its regulation, which suggest that telomeres may have acquired different additional functions in different organisms. Centromeres show less conservation than do telomeres.
ISSN:0959-437X
1879-0380
DOI:10.1016/0959-437X(94)90069-8