Epilepsia Partialis Continua: Follow-Up with 99mTc-HMPAO-SPECT

Abstract A three-year-old girl with epilepsia partialis continua involving the left side of the face and the left arm and leg was followed-up by 99m Tc-HMPAO-SPECT in addition to EEG and CT. Increased regional cerebral blood flow was found in the right Rolandic area in the early stage of the disease, when the CT was normal and the EEG showed marked right hemispheric slowing. Seven months later severe hypoperfusion, extending to the right frontotemporal region, and localised hyperperfusion in the right parietal area were observed by the 99m Tc-HMPAO-SPECT when CT detected right hemispheric atrophy and EEG recorded severe epileptic activity, involving even the contralateral areas. The 99m Tc-HMPAO-SPECT proved to be useful for the follow-up of the dynamics of the disease process.