Symptomatic spinal epidural lipomatosis in a patient with Cushing's disease

Spinal epidural lipomatosis (SEL) is a rare complication of iatrogenic Cushing's syndrome (CS).There is only one case reported of symptomatic SEL in association with endogenous CS. We present a patient with compressive myeloradiculopathy due to SEL and Cushing's disease and suggest that in...

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Veröffentlicht in:	Neurology 1995-12, Vol.45 (12), p.2281-2283
Hauptverfasser:	Sivakumar, Kumaraswamy, Sheinart, Kara, Lidov, Mika, Cohen, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenals. Adrenal axis. Renin-angiotensin system (diseases) Adult Biological and medical sciences Cushing Syndrome - complications Endocrinopathies Epidural Space Humans Lipomatosis - complications Lipomatosis - diagnosis Magnetic Resonance Imaging Male Medical sciences Myelography Nerve Compression Syndromes - etiology Non tumoral diseases. Target tissue resistance. Benign neoplasms Spinal Cord Compression - etiology Spinal Diseases - complications Spinal Diseases - diagnosis Spinal Nerve Roots Tomography, X-Ray Computed
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Zusammenfassung:	Spinal epidural lipomatosis (SEL) is a rare complication of iatrogenic Cushing's syndrome (CS).There is only one case reported of symptomatic SEL in association with endogenous CS. We present a patient with compressive myeloradiculopathy due to SEL and Cushing's disease and suggest that in SEL of hypercortisolism, the excess of corticosteroids is the stimulus for the growth of adipose tissue in the spinal canal and that treatment should be aimed at correcting the endocrine abnormality. NEUROLOGY 1995;452281-2283
ISSN:	0028-3878 1526-632X
DOI:	10.1212/WNL.45.12.2281