Signal transduction by β-catenin

Signal transduction by β-catenin

β-catenin participates in signal transduction and developmental patterning in Xenopus and Drosophila embryos as a component of the Wnt signaling pathway. Its signaling activity is distinct from its role in cadherin-mediated cell adhesion, and it probably acts either in the cytosol or in the nucleus....

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Veröffentlicht in:Current opinion in cell biology 1995-10, Vol.7 (5), p.634-640
1. Verfasser: Gumbiner, Barry M
Format: Artikel
Sprache:eng
Schlagworte:
Animals
beta Catenin
Cell Adhesion - physiology
Cell Division - physiology
Cytoskeletal Proteins - physiology
Signal Transduction - physiology
Trans-Activators
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Beschreibung
Zusammenfassung:β-catenin participates in signal transduction and developmental patterning in Xenopus and Drosophila embryos as a component of the Wnt signaling pathway. Its signaling activity is distinct from its role in cadherin-mediated cell adhesion, and it probably acts either in the cytosol or in the nucleus. The adenomatous polyposis coli tumor suppressor protein is also implicated in β-catenin signaling.
ISSN:0955-0674
1879-0410
DOI:10.1016/0955-0674(95)80104-9