Attachment and entry of infectious pancreatic necrosis virus (IPNV) into CHSE-214 cells

Infectious pancreatic necrosis virus (IPNV) attaches to CHSE-214 cells through two types of cell components: specific and non-specific ones. Competition experiments with inactivated IPNV showed that IPNV requires specific components to productively infect cells. Just a low amount of adsorbed IPNV en...

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Veröffentlicht in:	Archives of virology 1995-01, Vol.140 (10), p.1833-1840
Hauptverfasser:	KUZNAR, J, SOLER, M, FARIAS, G, ESPINOZA, J. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Birnaviridae - growth & development Birnaviridae Infections - physiopathology Cells, Cultured Endocytosis Fishes - microbiology Fundamental and applied biological sciences. Psychology Microbiology Neutralization Tests Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains RNA, Viral - biosynthesis Time Factors Virology
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Beschreibung
Zusammenfassung:	Infectious pancreatic necrosis virus (IPNV) attaches to CHSE-214 cells through two types of cell components: specific and non-specific ones. Competition experiments with inactivated IPNV showed that IPNV requires specific components to productively infect cells. Just a low amount of adsorbed IPNV enters the cell. After 20 minutes, part of the adsorbed IPNV was internalized into acid compartments. Also, the viruses adsorbed on the cell surface require similar periods of time to escape from the neutralization of antibodies.
ISSN:	0304-8608 1432-8798
DOI:	10.1007/BF01384345