Characterization and comparison of the polyclonal immune response to purified PLP and DM-20 in the lewis rat: Determination of a new antigenic determinant

Lewis rat polyclonal antibodies raised against pure PLP and DM-20 were characterized by indirect and competitive ELISA assays. Anti-PLP antibodies showed a good cross-reactivity with DM-20 and vice versa, suggesting that the chief B-cell epitopes are the same on both proteolipids. Three antigenic de...

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Veröffentlicht in:Neurochemistry international 1994-11, Vol.25 (5), p.433-440
Hauptverfasser: Klinguer, Christine, Trifilieff, Elisabeth
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Sprache:eng
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