The neuron as a mosaic of proteins

Today, molecular biology methods show that the neuron's functional properties are due to proteins in the membrane and cytoplasm. With the evidence not yet complete, it appears that there are already a great many such proteins. Thus it seems that our canonical neuron must be up-dated, it might e...

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Veröffentlicht in:Journal of physiology (Paris) 1994, Vol.88 (2), p.99-104
1. Verfasser: Kado, R.T.
Format: Artikel
Sprache:eng
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Zusammenfassung:Today, molecular biology methods show that the neuron's functional properties are due to proteins in the membrane and cytoplasm. With the evidence not yet complete, it appears that there are already a great many such proteins. Thus it seems that our canonical neuron must be up-dated, it might even be described today as a mosaic of proteins. In this view, the neuron produces its function (whatever that is) according to the arrangement of its molecules in the different parts of the neuron, its protein mosaic. In this paper, I will try to trace the evolution of the canonical neuron toward a protein mosaic and propose how we may use the mosaic to understand its function. (DBO)
ISSN:0928-4257
1769-7115
DOI:10.1016/0928-4257(94)90020-5