Does Paclitaxel Penetrate Into Brain Tumor Tissue?

Heimans and others argue that there may still be a rationale for paclitaxel, also in combination with radiotherapy, in the treatment of central nervous system malignancies. Egorin responds that more clinical evaluation is needed in this area.

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Bibliographische Detailangaben
Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1995-12, Vol.87 (23), p.1804-1805
Hauptverfasser:	HEIMAN, JAN J., TAPHOORN, MARTIN J. B., VERMORKEN, JAN B., EELTINK, CORINNE, WOLBERS, JOHN G., MEIJER, OTTO W. M., BEUNEN, Jos H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - pharmacokinetics Brain Brain - metabolism Brain Neoplasms - metabolism Drug therapy Humans Medical research Paclitaxel - pharmacokinetics Tumors
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Beschreibung
Zusammenfassung:	Heimans and others argue that there may still be a rationale for paclitaxel, also in combination with radiotherapy, in the treatment of central nervous system malignancies. Egorin responds that more clinical evaluation is needed in this area.
ISSN:	0027-8874 1460-2105
DOI:	10.1093/jnci/87.23.1804-a