ENDOTOXIN TESTING

ENDOTOXIN TESTING

SUMMARY Parenterals, sterile preparations intended to be injected in man or animal, should be free from pyrogenic substances which are able to raise the thermostatic setting in the hypothalamus. This article gives an up‐to‐date review of the principal detection and quantification methods for these a...

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Veröffentlicht in:Journal of clinical pharmacy and therapeutics 1987-08, Vol.12 (4), p.223-235
Hauptverfasser: Vanhaecke, E., Pijck, J., Vuye, A.
Format: Artikel
Sprache:eng
Schlagworte:
Endotoxins - analysis
Fever - chemically induced
Humans
Limulus Test
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Beschreibung
Zusammenfassung:SUMMARY Parenterals, sterile preparations intended to be injected in man or animal, should be free from pyrogenic substances which are able to raise the thermostatic setting in the hypothalamus. This article gives an up‐to‐date review of the principal detection and quantification methods for these agents, with special attention on the chromogenic Limulus Amebocyte Lysate assay.
ISSN:0269-4727
1365-2710
DOI:10.1111/j.1365-2710.1987.tb00531.x