Variant translocation t(15q;17q) accompanying a promyelocytic accelerated phase of Ph-positive chronic myeloid leukemia

One case of Philadelphia-positive chronic myeloid leukemia showed a high promyelocytic component associated with a variant t(15q−,17q+) translocation. A key role for chromosome #17 in the promyelocytic proliferation and/or differentiation is emphasized.

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Bibliographische Detailangaben
Veröffentlicht in:	Cancer genetics and cytogenetics 1987-10, Vol.28 (2), p.349-352
Hauptverfasser:	Louwagie, A.C., Mecucci, C., Criel, A., Van Hoof, A., Van Den Berghe, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Blast Crisis - genetics Blast Crisis - pathology Chromosome Banding Chromosomes, Human, Pair 15 Chromosomes, Human, Pair 17 Genetic Markers Hematologic and hematopoietic diseases Humans Karyotyping Leukemia, Myeloid - genetics Leukemia, Myeloid - pathology Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - pathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Philadelphia Chromosome Translocation, Genetic
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Beschreibung
Zusammenfassung:	One case of Philadelphia-positive chronic myeloid leukemia showed a high promyelocytic component associated with a variant t(15q−,17q+) translocation. A key role for chromosome #17 in the promyelocytic proliferation and/or differentiation is emphasized.
ISSN:	0165-4608 1873-4456
DOI:	10.1016/0165-4608(87)90222-6