Sesquiterpene/Quinol from a New Zealand Liverwort, Riccardia crassa

A new sesquiterpene/quinol, with mild cytotoxic and antibacterial activity, has been isolated from a New Zealand collection of the liverwort Riccardia crassa. The structure of this compound, riccardiphenol C [3], was established by nmr spectroscopy. Closely related compounds previously isolated from...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1995-07, Vol.58 (7), p.1131-1135
Hauptverfasser:	Perry, Nigel B, Foster, Lysa M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents Anti-Infective Agents - isolation & purification Anti-Infective Agents - pharmacology ANTIBACTERIAL PROPERTIES ANTIMICROBIAL PROPERTIES Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Bacteria - drug effects Benzopyrans - isolation & purification Benzopyrans - pharmacology BRYOPHYTA CHEMICAL COMPOSITION CHEMISTRY CHIMIE COMPOSICION QUIMICA COMPOSITION CHIMIQUE CYTOTOXIC COMPOUNDS Drug Screening Assays, Antitumor ESPECTROMETRIA Fungi - drug effects Humans Magnetic Resonance Spectroscopy Mice Microbial Sensitivity Tests MOLECULAR CONFORMATION MOLECULAR STRUCTURE NEW ZEALAND NOUVELLE ZELANDE NUEVA ZELANDIA Plants, Medicinal - chemistry PROPIEDADES ANTIMICROBIANAS PROPRIETE ANTIMICROBIENNE QUIMICA RICCARDIPHENOL Sesquiterpenes - isolation & purification Sesquiterpenes - pharmacology SESQUITERPENOIDE SESQUITERPENOIDS SESQUITERPENOS SPECTRAL ANALYSIS SPECTROMETRIE SPECTROMETRY STEREOCHEMISTRY SUBSTANCE TOXIQUE SUSTANCIAS TOXICAS TOXIC SUBSTANCES Tumor Cells, Cultured
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Beschreibung
Zusammenfassung:	A new sesquiterpene/quinol, with mild cytotoxic and antibacterial activity, has been isolated from a New Zealand collection of the liverwort Riccardia crassa. The structure of this compound, riccardiphenol C [3], was established by nmr spectroscopy. Closely related compounds previously isolated from a Japanese collection of R. crassa were not detected in this collection.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np50121a027