CD23 and B-cell activation

The past year has seen the publication of significant new findings on the regulation of CD23 expression, the precise interaction of CD23 with CD21 and its functional consequences. Moreover, new advances have been made in unravelling the biochemical network of events downstream from the triggering of...

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Veröffentlicht in:	Current opinion in immunology 1995, Vol.7 (3), p.355-359
Hauptverfasser:	Bonnefoy, Jean-Yves, Lecoanet-Henchoz, Sybille, Aubry, Jean-Pierre, Gauchat, Jean-Francois, Graber, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B-Lymphocytes - immunology B-Lymphocytes - physiology Cell Adhesion Molecules - immunology Humans Immunoglobulin E - biosynthesis Lymphocyte Activation Mice Mice, Transgenic Receptors, IgE - immunology Signal Transduction
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The past year has seen the publication of significant new findings on the regulation of CD23 expression, the precise interaction of CD23 with CD21 and its functional consequences. Moreover, new advances have been made in unravelling the biochemical network of events downstream from the triggering of CD23 in human B cells. Analyses of the properties of CD23-deficient mice have demonstrated a link between lgE regulation and CD23 in vivo.
ISSN:	0952-7915 1879-0372
DOI:	10.1016/0952-7915(95)80110-3