Involvement of the sympathetic nervous system in lipolytic activity in brown adipose tissue of cold acclimated rats

1. 1. In cold acclimated rats, in vitro, NE led to a significant increase in release of FFA and glycerol in denervated IBAT. 2. 2. In vivo, study of arteriovenous differences showed that the denervated BAT loses its full capacity to utilize FFA and glycerol released by NE. 3. 3. After denervation an...

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Veröffentlicht in:	Comparative biochemistry and physiology. A, Comparative physiology Comparative physiology, 1987, Vol.87 (1), p.197-203
Hauptverfasser:	Laury, M.C, Chapey, M.F, Portet, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acclimatization Adipose Tissue, Brown - drug effects Adipose Tissue, Brown - innervation Adipose Tissue, Brown - physiology Animals Biological and medical sciences Body Weight Cold Temperature Fundamental and applied biological sciences. Psychology Lipolysis - drug effects Male Norepinephrine - pharmacology Organ Size Rats Sympathetic Nervous System - physiology Thermoregulation. Hibernation. Estivation. Ecophysiology and environmental effects Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Zusammenfassung:	1. 1. In cold acclimated rats, in vitro, NE led to a significant increase in release of FFA and glycerol in denervated IBAT. 2. 2. In vivo, study of arteriovenous differences showed that the denervated BAT loses its full capacity to utilize FFA and glycerol released by NE. 3. 3. After denervation an increase of blood flow in Sulzer's vein was observed. This effect appeared immediately after intervention whereas the effect on fat metabolism appeared later. 4. 4. In cold acclimated rats, the sympathetic nervous system appears to be an important regulator of fatty acid metabolism in BAT.
ISSN:	0300-9629
DOI:	10.1016/0300-9629(87)90446-4