Evaluation of myocardial perfusion and function by single photon emission computed tomography
Although planar radionuclide techniques provide accurate, noninvasive measurements of myocardial perfusion and function that are of proven clinical value in the evaluation of the cardiac patient, they are limited by poor object contrast and superimposition of surrounding structures. Due to incomplet...
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| Veröffentlicht in: | Semin. Nucl. Med.; (United States) 1987-07, Vol.17 (3), p.200-213 |
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| creator | Cerqueira, Manuel D. Harp, George D. Ritchie, James L. |
| description | Although planar radionuclide techniques provide accurate, noninvasive measurements of myocardial perfusion and function that are of proven clinical value in the evaluation of the cardiac patient, they are limited by poor object contrast and superimposition of surrounding structures. Due to incomplete angular sampling and significant longitudinal distortion, limited angle tomography did not solve these problems. Single photon emission computed tomography (SPECT) can acquire scintilation information over very small angles of rotation and, thus, improve both object contrast and delineation of overlying or adjacent structures without distortion. The early SPECT systems were cumbersome, dependent on individual user developed software, and had extremely long acquisition and processing time. Improved camera design, new software algorithms, and the use of array processors have simplified and standardized quality control, decreased processing time, and minimized the number of user interventions. New image display formats and quantitative methods of analysis have made interpretation less cumbersome, more reliable and highly reproducible. Cardiac SPECT has been used with thallium-201 and gated blood pool imaging in both research and clinical applications and shown an improvement over planar methods of acquisition. |
| doi_str_mv | 10.1016/S0001-2998(87)80034-X |
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Due to incomplete angular sampling and significant longitudinal distortion, limited angle tomography did not solve these problems. Single photon emission computed tomography (SPECT) can acquire scintilation information over very small angles of rotation and, thus, improve both object contrast and delineation of overlying or adjacent structures without distortion. The early SPECT systems were cumbersome, dependent on individual user developed software, and had extremely long acquisition and processing time. Improved camera design, new software algorithms, and the use of array processors have simplified and standardized quality control, decreased processing time, and minimized the number of user interventions. New image display formats and quantitative methods of analysis have made interpretation less cumbersome, more reliable and highly reproducible. Cardiac SPECT has been used with thallium-201 and gated blood pool imaging in both research and clinical applications and shown an improvement over planar methods of acquisition.</description><identifier>ISSN: 0001-2998</identifier><identifier>EISSN: 1558-4623</identifier><identifier>DOI: 10.1016/S0001-2998(87)80034-X</identifier><identifier>PMID: 3303340</identifier><identifier>CODEN: SMNMAB</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics ; ALGORITHMS ; BETA DECAY RADIOISOTOPES ; Biological and medical sciences ; BODY ; CARDIOVASCULAR DISEASES ; CARDIOVASCULAR SYSTEM ; COMPUTERIZED TOMOGRAPHY ; CONTROL ; Coronary Disease - diagnostic imaging ; COUNTING TECHNIQUES ; DAYS LIVING RADIOISOTOPES ; DIAGNOSIS ; DIAGNOSTIC TECHNIQUES ; DISEASES ; DYNAMIC FUNCTION STUDIES ; ELECTRON CAPTURE RADIOISOTOPES ; EMISSION COMPUTED TOMOGRAPHY ; HEART ; Heart - diagnostic imaging ; HEAVY NUCLEI ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; ISOMERIC TRANSITION ISOTOPES ; ISOTOPES ; MATHEMATICAL LOGIC ; Medical sciences ; MYOCARDIAL INFARCTION ; Myocardial Infarction - diagnostic imaging ; NUCLEI ; ODD-EVEN NUCLEI ; ORGANS ; QUALITY CONTROL ; RADIOISOTOPE SCANNING ; RADIOISOTOPES ; RADIOLOGY AND NUCLEAR MEDICINE ; Radionuclide investigations ; SCINTISCANNING ; SECONDS LIVING RADIOISOTOPES ; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY ; Software ; Thallium ; THALLIUM 201 ; THALLIUM ISOTOPES ; TOMOGRAPHY ; Tomography, Emission-Computed - instrumentation ; Tomography, Emission-Computed - methods</subject><ispartof>Semin. 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Nucl. Med.; (United States)</title><addtitle>Semin Nucl Med</addtitle><description>Although planar radionuclide techniques provide accurate, noninvasive measurements of myocardial perfusion and function that are of proven clinical value in the evaluation of the cardiac patient, they are limited by poor object contrast and superimposition of surrounding structures. Due to incomplete angular sampling and significant longitudinal distortion, limited angle tomography did not solve these problems. Single photon emission computed tomography (SPECT) can acquire scintilation information over very small angles of rotation and, thus, improve both object contrast and delineation of overlying or adjacent structures without distortion. The early SPECT systems were cumbersome, dependent on individual user developed software, and had extremely long acquisition and processing time. Improved camera design, new software algorithms, and the use of array processors have simplified and standardized quality control, decreased processing time, and minimized the number of user interventions. New image display formats and quantitative methods of analysis have made interpretation less cumbersome, more reliable and highly reproducible. Cardiac SPECT has been used with thallium-201 and gated blood pool imaging in both research and clinical applications and shown an improvement over planar methods of acquisition.</description><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics</subject><subject>ALGORITHMS</subject><subject>BETA DECAY RADIOISOTOPES</subject><subject>Biological and medical sciences</subject><subject>BODY</subject><subject>CARDIOVASCULAR DISEASES</subject><subject>CARDIOVASCULAR SYSTEM</subject><subject>COMPUTERIZED TOMOGRAPHY</subject><subject>CONTROL</subject><subject>Coronary Disease - diagnostic imaging</subject><subject>COUNTING TECHNIQUES</subject><subject>DAYS LIVING RADIOISOTOPES</subject><subject>DIAGNOSIS</subject><subject>DIAGNOSTIC TECHNIQUES</subject><subject>DISEASES</subject><subject>DYNAMIC FUNCTION STUDIES</subject><subject>ELECTRON CAPTURE RADIOISOTOPES</subject><subject>EMISSION COMPUTED TOMOGRAPHY</subject><subject>HEART</subject><subject>Heart - diagnostic imaging</subject><subject>HEAVY NUCLEI</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>ISOMERIC TRANSITION ISOTOPES</subject><subject>ISOTOPES</subject><subject>MATHEMATICAL LOGIC</subject><subject>Medical sciences</subject><subject>MYOCARDIAL INFARCTION</subject><subject>Myocardial Infarction - diagnostic imaging</subject><subject>NUCLEI</subject><subject>ODD-EVEN NUCLEI</subject><subject>ORGANS</subject><subject>QUALITY CONTROL</subject><subject>RADIOISOTOPE SCANNING</subject><subject>RADIOISOTOPES</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radionuclide investigations</subject><subject>SCINTISCANNING</subject><subject>SECONDS LIVING RADIOISOTOPES</subject><subject>SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY</subject><subject>Software</subject><subject>Thallium</subject><subject>THALLIUM 201</subject><subject>THALLIUM ISOTOPES</subject><subject>TOMOGRAPHY</subject><subject>Tomography, Emission-Computed - instrumentation</subject><subject>Tomography, Emission-Computed - methods</subject><issn>0001-2998</issn><issn>1558-4623</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkFuL1DAUgIMo6-zoT1goIqIP1aRpbk-LLLsqLPigwr5ISNOTnUib1CRdmH9vOzPMq08HzvnO7UPoiuCPBBP-6QfGmNSNUvK9FB8kxrStH56hDWFM1i1v6HO0OSMv0WXOfzBuGFPsAl1Qiilt8Qb9vn0yw2yKj6GKrhr30ZrUezNUEyQ35zVvQl-5OdgD1O2r7MPjANW0i2VJwOjzAbNxnOYCfVXiGB-TmXb7V-iFM0OG16e4Rb_ubn_efK3vv3_5dvP5vrYt4aXupJBEdVj1jVXUUgZckFZxKxQ4ThxvjeAYg2kbhbmTzLU9dSDBStUBZXSL3hznxly8ztYXsDsbQwBbNFNCkEXPFr07QlOKf2fIRS-XWxgGEyDOWQvBGymIWkB2BG2KOSdwekp-NGmvCdare31wr1exWgp9cK8flr6r04K5G6E_d51kL_W3p7rJ1gwumWB9PmOSNlgoumDXRwwWY08e0voQBAu9T-s_ffT_OeQfHYqhZw</recordid><startdate>19870701</startdate><enddate>19870701</enddate><creator>Cerqueira, Manuel D.</creator><creator>Harp, George D.</creator><creator>Ritchie, James L.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>19870701</creationdate><title>Evaluation of myocardial perfusion and function by single photon emission computed tomography</title><author>Cerqueira, Manuel D. ; Harp, George D. ; Ritchie, James L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c416t-b87819b09d2c93c35e671496c79ef61f64a7600ea42906f85f4d3fe8ec89be353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>550601 - Medicine- Unsealed Radionuclides in Diagnostics</topic><topic>ALGORITHMS</topic><topic>BETA DECAY RADIOISOTOPES</topic><topic>Biological and medical sciences</topic><topic>BODY</topic><topic>CARDIOVASCULAR DISEASES</topic><topic>CARDIOVASCULAR SYSTEM</topic><topic>COMPUTERIZED TOMOGRAPHY</topic><topic>CONTROL</topic><topic>Coronary Disease - diagnostic imaging</topic><topic>COUNTING TECHNIQUES</topic><topic>DAYS LIVING RADIOISOTOPES</topic><topic>DIAGNOSIS</topic><topic>DIAGNOSTIC TECHNIQUES</topic><topic>DISEASES</topic><topic>DYNAMIC FUNCTION STUDIES</topic><topic>ELECTRON CAPTURE RADIOISOTOPES</topic><topic>EMISSION COMPUTED TOMOGRAPHY</topic><topic>HEART</topic><topic>Heart - diagnostic imaging</topic><topic>HEAVY NUCLEI</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>ISOMERIC TRANSITION ISOTOPES</topic><topic>ISOTOPES</topic><topic>MATHEMATICAL LOGIC</topic><topic>Medical sciences</topic><topic>MYOCARDIAL INFARCTION</topic><topic>Myocardial Infarction - diagnostic imaging</topic><topic>NUCLEI</topic><topic>ODD-EVEN NUCLEI</topic><topic>ORGANS</topic><topic>QUALITY CONTROL</topic><topic>RADIOISOTOPE SCANNING</topic><topic>RADIOISOTOPES</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radionuclide investigations</topic><topic>SCINTISCANNING</topic><topic>SECONDS LIVING RADIOISOTOPES</topic><topic>SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY</topic><topic>Software</topic><topic>Thallium</topic><topic>THALLIUM 201</topic><topic>THALLIUM ISOTOPES</topic><topic>TOMOGRAPHY</topic><topic>Tomography, Emission-Computed - instrumentation</topic><topic>Tomography, Emission-Computed - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cerqueira, Manuel D.</creatorcontrib><creatorcontrib>Harp, George D.</creatorcontrib><creatorcontrib>Ritchie, James L.</creatorcontrib><creatorcontrib>Veterans Administration Medical Center, Seattle, WA</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Semin. Nucl. Med.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cerqueira, Manuel D.</au><au>Harp, George D.</au><au>Ritchie, James L.</au><aucorp>Veterans Administration Medical Center, Seattle, WA</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of myocardial perfusion and function by single photon emission computed tomography</atitle><jtitle>Semin. Nucl. Med.; (United States)</jtitle><addtitle>Semin Nucl Med</addtitle><date>1987-07-01</date><risdate>1987</risdate><volume>17</volume><issue>3</issue><spage>200</spage><epage>213</epage><pages>200-213</pages><issn>0001-2998</issn><eissn>1558-4623</eissn><coden>SMNMAB</coden><abstract>Although planar radionuclide techniques provide accurate, noninvasive measurements of myocardial perfusion and function that are of proven clinical value in the evaluation of the cardiac patient, they are limited by poor object contrast and superimposition of surrounding structures. Due to incomplete angular sampling and significant longitudinal distortion, limited angle tomography did not solve these problems. Single photon emission computed tomography (SPECT) can acquire scintilation information over very small angles of rotation and, thus, improve both object contrast and delineation of overlying or adjacent structures without distortion. The early SPECT systems were cumbersome, dependent on individual user developed software, and had extremely long acquisition and processing time. Improved camera design, new software algorithms, and the use of array processors have simplified and standardized quality control, decreased processing time, and minimized the number of user interventions. New image display formats and quantitative methods of analysis have made interpretation less cumbersome, more reliable and highly reproducible. Cardiac SPECT has been used with thallium-201 and gated blood pool imaging in both research and clinical applications and shown an improvement over planar methods of acquisition.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>3303340</pmid><doi>10.1016/S0001-2998(87)80034-X</doi><tpages>14</tpages></addata></record> |
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| ispartof | Semin. Nucl. Med.; (United States), 1987-07, Vol.17 (3), p.200-213 |
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| subjects | 550601 - Medicine- Unsealed Radionuclides in Diagnostics ALGORITHMS BETA DECAY RADIOISOTOPES Biological and medical sciences BODY CARDIOVASCULAR DISEASES CARDIOVASCULAR SYSTEM COMPUTERIZED TOMOGRAPHY CONTROL Coronary Disease - diagnostic imaging COUNTING TECHNIQUES DAYS LIVING RADIOISOTOPES DIAGNOSIS DIAGNOSTIC TECHNIQUES DISEASES DYNAMIC FUNCTION STUDIES ELECTRON CAPTURE RADIOISOTOPES EMISSION COMPUTED TOMOGRAPHY HEART Heart - diagnostic imaging HEAVY NUCLEI Humans Investigative techniques, diagnostic techniques (general aspects) ISOMERIC TRANSITION ISOTOPES ISOTOPES MATHEMATICAL LOGIC Medical sciences MYOCARDIAL INFARCTION Myocardial Infarction - diagnostic imaging NUCLEI ODD-EVEN NUCLEI ORGANS QUALITY CONTROL RADIOISOTOPE SCANNING RADIOISOTOPES RADIOLOGY AND NUCLEAR MEDICINE Radionuclide investigations SCINTISCANNING SECONDS LIVING RADIOISOTOPES SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY Software Thallium THALLIUM 201 THALLIUM ISOTOPES TOMOGRAPHY Tomography, Emission-Computed - instrumentation Tomography, Emission-Computed - methods |
| title | Evaluation of myocardial perfusion and function by single photon emission computed tomography |
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