A NEW ANTITUMOR ANTIBIOTIC, FR-900482: I. TAXONOMIC STUDIES ON THE PRODUCING STRAIN: A NEW SPECIES OF THE GENUS STREPTOMYCES

A new species in the genus Streptomyces, for which the name Streptomyces sandaensis sp. nov. is proposed, is described. Soil isolate strain No. 6897 (FERM-P 7654), produces a new antitumor substance FR-900482. The strain has a gray to red spore mass color, Rectus Flexibilis to Retinaculum-Apertum sp...

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Veröffentlicht in:	Journal of antibiotics 1987/05/25, Vol.40(5), pp.589-593
Hauptverfasser:	IWAMI, MORITA, KIYOTO, SUMIO, TERANO, HIROSHI, KOHSAKA, MASANOBU, AOKI, HATSUO, IMANAKA, HIROSHI
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics, Antineoplastic - analysis Antiviral drugs Biological and medical sciences Biotechnology Bridged Bicyclo Compounds - analysis Carbon - metabolism Cell Wall - analysis Culture Media Fundamental and applied biological sciences. Psychology Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Oxazines Production of active biomolecules Soil Microbiology Spores, Bacterial - analysis Streptomyces - analysis Streptomyces - classification Streptomyces - physiology
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Zusammenfassung:	A new species in the genus Streptomyces, for which the name Streptomyces sandaensis sp. nov. is proposed, is described. Soil isolate strain No. 6897 (FERM-P 7654), produces a new antitumor substance FR-900482. The strain has a gray to red spore mass color, Rectus Flexibilis to Retinaculum-Apertum spore chain morphology, smooth spores, and is nonchromogenic. Strain No. 6897 is closely related to Streptomyces aburaviensis and Streptomyces nitrosporeus. But, there are many differences in cultural characteristics and in the utilization of carbohydrates.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.40.589