Clinical Study on Tsutsugamushi Disease in Miyazaki District

We clinically examined 48 cases with tsutsugamushi disease occurred in Miyazaki district during 1984. In clinical sign, eschar was detected in all cases. Systemic lymphadenopathy and hepatomegaly were observed in the cases after 7 days from onset. Laboratory examination revealed leukopenia and minimal or moderate liver dysfunction. Of the serotypes of infected Rickettsia tsutsugamushi which were defined in 31 cases by antibody analysis, 26 were Irie and 5 were Hirano type. There was no difference in clinical feature between two groups of patients. Comparing our cases with the cases in Miyazaki during 1957-1964 and the cases reported from other district in Japan, we concluded that there was significantly no difference in clinical findings except bleeding tendency among them.