Inhibitory activity of sphingomyelin on hemolytic activity of coelomic fluid of Holothuria polii (Echinodermata)

The hemolytic activity of coelomic fluid from Holothuria polii is specifically inhibited by sphingomyelin. This phospholipid is the constituent of the membrane which probably interacts with the hemolysin thereby leading to the lysis.

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Bibliographische Detailangaben
Veröffentlicht in:	Developmental and comparative immunology 1987, Vol.11 (1), p.29-35
Hauptverfasser:	CANICATTI, C, PARRINELLO, N, ARIZZA, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria - immunology Biological and medical sciences Body Fluids - immunology Cholesterol coelom coelomic fluids Complement Inactivator Proteins - pharmacology Echinodermata Echinodermata - immunology Erythrocytes - immunology Fundamental and applied biological sciences. Psychology hemolysis Hemolysis - drug effects Holothuria polii immunology inhibitors Invertebrates Marine myelin Phospholipids - pharmacology Sea Cucumbers - immunology Sphingomyelin Phosphodiesterase - metabolism Sphingomyelins - pharmacology
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Beschreibung
Zusammenfassung:	The hemolytic activity of coelomic fluid from Holothuria polii is specifically inhibited by sphingomyelin. This phospholipid is the constituent of the membrane which probably interacts with the hemolysin thereby leading to the lysis.
ISSN:	0145-305X 1879-0089
DOI:	10.1016/0145-305X(87)90005-X