Measurement of acetylcholine receptor concentration in skeletal muscle from a patient with multiple sclerosis and resistance to atracurium

Measurement of acetylcholine receptor concentration in skeletal muscle from a patient with multiple sclerosis and resistance to atracurium

The authors describe a patient with multiple sclerosis who exhibited both clinical resistance to atracurium and an abnormal elevation of the number of skeletal muscle acetylcholine receptors.

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Veröffentlicht in:Anesthesiology (Philadelphia) 1987-06, Vol.66 (6), p.837-839
Hauptverfasser: BRETT, R. S, SCHMIDT, J. H, GAGE, J. S, SCHARTEL, S. A, POPPERS, P. J
Format: Artikel
Sprache:eng
Schlagworte:
acetylcholine
Adult
Anesthetics. Neuromuscular blocking agents
Atracurium - pharmacology
Biological and medical sciences
Drug Resistance
Female
Humans
man
Medical sciences
multiple sclerosis
Multiple Sclerosis - physiopathology
Muscles - analysis
Neuromuscular Junction - drug effects
Neuropharmacology
Pharmacology. Drug treatments
Receptors, Cholinergic - analysis
skeletal muscle
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Beschreibung
Zusammenfassung:The authors describe a patient with multiple sclerosis who exhibited both clinical resistance to atracurium and an abnormal elevation of the number of skeletal muscle acetylcholine receptors.
ISSN:0003-3022
1528-1175
DOI:10.1097/00000542-198706000-00025