Lipid Composition and Orientation in Secretory Vesicles

Lipid Composition and Orientation in Secretory Vesicles

The exocytotic release of hormones and neurotransmitters from subcellular storage vesicles begins with the elevation of cytosolic calcium concentration and ends with the storage vesicle open to the cell exterior through fusion of the vesicle membrane with the plasma membrane. The function, if not th...

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Veröffentlicht in:Annals of the New York Academy of Sciences 1987, Vol.493 (1), p.92-100
1. Verfasser: WESTHEAD, EDWARD W.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Brain Chemistry
Chromaffin Granules - analysis
Cytoplasmic Granules - analysis
Fatty Acids - analysis
Humans
Intracellular Membranes - analysis
lipid composition
membrane fusion
Membrane Lipids - analysis
Phospholipids - analysis
reviews
Species Specificity
Synaptic Vesicles - analysis
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Beschreibung
Zusammenfassung:The exocytotic release of hormones and neurotransmitters from subcellular storage vesicles begins with the elevation of cytosolic calcium concentration and ends with the storage vesicle open to the cell exterior through fusion of the vesicle membrane with the plasma membrane. The function, if not the intention, of this report will be to focus attention on how little we know about the role of the membrane lipids in the fusion of the two membranes.
ISSN:0077-8923
1749-6632
DOI:10.1111/j.1749-6632.1987.tb27186.x