MAST CELLS, IgE CONTAINING CELLS AND TISSUE HISTAMINE CONTENTS IN NORMAL MUCOSA OF EACH PART OF THE LARGE INTESTINE

We investigated mast cells, IgE containing cells and tissue histamine contents of 53 samples of 14 healthy persons. It was concluded that the number of mast cells, the number on IgE containing cells and tissue histamine contents in ascending colon, transverse colon, descending colon, sigmoid colon and rectum were not significant. In addition, a positive correlation between the number of mast cells existed in the lamina propria mucosae and histamine contents of colonic mucosa was observed. As the results, mast cells, IgE containing cells and tissue histamine contents in normal mucosa of each part of the large intestine distributed almost evenly from ascending colon to rectum, furthermore it was suggested that tissue histamine contents might exist partly in the mast cells.