hSRY: molecular gender bender

The recently published solution structure of the DNA-binding domain of hSRY in complex with a DNA octamer offers insight into the sex reversal effects of mutations in hSRY and the interaction of all HMG boxes with DNA.

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Bibliographische Detailangaben
Veröffentlicht in:	Structure 1995-07, Vol.3 (7), p.631-633
Hauptverfasser:	Bramham, Janice, Norman, David G
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Crystallography, X-Ray DNA-Binding Proteins - chemistry High Mobility Group Proteins - chemistry Humans Male Models, Molecular Nuclear Proteins Prejudice Protein Structure, Secondary Sex-Determining Region Y Protein Transcription Factors - chemistry
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The recently published solution structure of the DNA-binding domain of hSRY in complex with a DNA octamer offers insight into the sex reversal effects of mutations in hSRY and the interaction of all HMG boxes with DNA.
ISSN:	0969-2126 1878-4186
DOI:	10.1016/S0969-2126(01)00196-4