Tissue penetration and metabolism of ciprofloxacin

The tissue penetration of ciprofloxacin was studied by two methods. Penetration into inflammatory fluid following oral administration (500 mg) was 117 percent; following intravenous administration (100 mg), penetration was 121 percent. The penetration of ciprofloxacin into uninflamed peritoneum foll...

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Veröffentlicht in:	The American journal of medicine 1987-04, Vol.82 (4A), p.103-107
Hauptverfasser:	Wise, R, Donovan, I A
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Aged Biological Availability Blister - metabolism Body Fluids - metabolism Ciprofloxacin - administration & dosage Ciprofloxacin - metabolism Humans Inflammation - metabolism Injections, Intravenous Kinetics Male Middle Aged Peritoneal Cavity - metabolism
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Zusammenfassung:	The tissue penetration of ciprofloxacin was studied by two methods. Penetration into inflammatory fluid following oral administration (500 mg) was 117 percent; following intravenous administration (100 mg), penetration was 121 percent. The penetration of ciprofloxacin into uninflamed peritoneum following intravenous administration (100 mg) was 95 percent.
ISSN:	0002-9343