PB-5266 A, B AND C, NEW MONOBACTAMS: I. TAXONOMY, FERMENTATION AND ISOLATION

New monobactams, PB-5266 A, B and C were isolated from the culture filtrate of Cytophaga johnsonae PB-5266 by various types of column chromatography and preparative reversephase HPLC. PB-5266 A, B and C exhibited weak antibacterial activity against a sensitive mutant of Escherichia coli to β-lactam...

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Veröffentlicht in:	Journal of antibiotics 1987/02/25, Vol.40(2), pp.135-138
Hauptverfasser:	KATO, TOSHIYUKI, HINOO, HIROSHI, SHOJI, JUN'ICHI, MATSUMOTO, KOICHI, TANIMOTO, TATSUO, HATTORI, TERUO, HIROOKA, KEIICHIRO, KONDO, EIJI
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - isolation & purification Antibacterial agents Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Biochemical Phenomena Biochemistry Biological and medical sciences Biotechnology Chromatography Cytophaga - analysis Cytophaga - classification Cytophaga - physiology Fundamental and applied biological sciences. Psychology Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Medical sciences Monobactams - isolation & purification Pharmacology. Drug treatments Production of active biomolecules
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Zusammenfassung:	New monobactams, PB-5266 A, B and C were isolated from the culture filtrate of Cytophaga johnsonae PB-5266 by various types of column chromatography and preparative reversephase HPLC. PB-5266 A, B and C exhibited weak antibacterial activity against a sensitive mutant of Escherichia coli to β-lactam antibiotics.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.40.135