Molecular Cloning of ID4, a Novel Dominant Negative Helix-Loop-Helix Human Gene on Chromosome 6p21.3-p22

Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate the expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent upon formation of homo- and/or heterodimers. Dominant negative HLH proteins (Id-...

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Veröffentlicht in:	Genomics 1995-05, Vol.27 (1), p.200-203
Hauptverfasser:	Pagliuca, Alfredo, Bartoli, Paola Cannada, Saccone, Salvatore, Della Valle, Giuliano, Lania, Luigi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biological and medical sciences BIOLOGY AND MEDICINE, BASIC STUDIES Chromosome Mapping Chromosomes, Human, Pair 6 Creatine Kinase - genetics DNA, Complementary - genetics DNA-Binding Proteins DNA-CLONING Enhancer Elements, Genetic Fundamental and applied biological sciences. Psychology GENES Genes, Dominant Genes, Reporter Genes. Genome GENETIC MAPPING HeLa Cells Helix-Loop-Helix Motifs - genetics HUMAN CHROMOSOME 6 Humans Inhibitor of Differentiation Proteins Molecular and cellular biology Molecular genetics Molecular Sequence Data MyoD Protein - antagonists & inhibitors Proteins - genetics Recombinant Fusion Proteins - metabolism RNA, Messenger - genetics Sequence Alignment Sequence Homology, Amino Acid TRANSCRIPTION FACTORS Transfection
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