MULUNDOCANDIN, A NEW LIPOPEPTIDE ANTIBIOTIC: II. STRUCTURE ELUCIDATION

The structure of a new antifungal antibiotic, mulundocandin, C48H77N7O16, was elucidated by high field NMR experiments e.g., homo- and heteronuclear correlation spectra, distortionless enhancement by polarization transfer (DEPT) spectra as well as nuclear Overhauser effect. The compound is a lipopep...

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Veröffentlicht in:	Journal of antibiotics 1987/03/25, Vol.40(3), pp.281-289
Hauptverfasser:	MUKHOPADHYAY, TRIPTIKUMAR, GANGULI, B. N., FEHLHABER, H. W., KOGLER, H., VERTESY, L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal Agents - isolation & purification Biological and medical sciences Chemical Phenomena Chemistry Chromatography, High Pressure Liquid Echinocandins Gas Chromatography-Mass Spectrometry General pharmacology Magnetic Resonance Spectroscopy Medical sciences Peptides, Cyclic - isolation & purification Pharmacology. Drug treatments Physicochemical properties. Structure-activity relationships
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Zusammenfassung:	The structure of a new antifungal antibiotic, mulundocandin, C48H77N7O16, was elucidated by high field NMR experiments e.g., homo- and heteronuclear correlation spectra, distortionless enhancement by polarization transfer (DEPT) spectra as well as nuclear Overhauser effect. The compound is a lipopeptide antibiotic belonging to the echinocandin class.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.40.281