Follow-up of 30 pregnancies after embryo cryopreservation

Objective: In an observational follow-up study, the pregnancy outcome of the first 30 women who conceived after transfer of cryopreserved embryos was evaluated. Study design: The main outcome measures were duration and complications of pregnancy, mode of delivery, complications during and after childbirth, birthweight, Apgar score, and congenital anomalies. Twenty-six pregnancies ended in birth of one ( n = 22) or more ( n = 4) infants with a cesarean section rate of 23%. Of the singleton pregnancies 77% were uncomplicated, but there was a high incidence of breech presentation (14%). Infant birthweight tended to be above average with 45% of singletons weighing more than the 75 th centile of weight for gestation. There were no major congenital deformations. The results of our embryo cryopreservation program are encouraging, but sustained follow-up of such pregnancies and infants is needed.