Isolated leukemia cutis—A case report

A 67‐year‐old woman with acute myelomonocytic leukemia had a clinical course characterized by the initial appearance of leukemia cutis without bone marrow involvement. When marrow involvement subsequently occurred, induction chemotherapy cleared all manifestations of the illness. Shortly thereafter,...

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Veröffentlicht in:	American journal of hematology 1987-04, Vol.24 (4), p.437-439
Hauptverfasser:	Haubenstock, A., Zalusky, R., Ghali, V. S., Mernick, M. H., Malamud, S. C., Stein, J. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	6‐thioguanine acute myelomonocytic leukemia Aged Biological and medical sciences Bone Marrow - drug effects Bone Marrow - pathology Female Hematologic and hematopoietic diseases Humans Leukemia - complications Leukemia - pathology Leukemia, Myeloid, Acute - complications Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Medical sciences Skin Neoplasms - complications Skin Neoplasms - drug therapy Skin Neoplasms - pathology Thioguanine - therapeutic use
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Zusammenfassung:	A 67‐year‐old woman with acute myelomonocytic leukemia had a clinical course characterized by the initial appearance of leukemia cutis without bone marrow involvement. When marrow involvement subsequently occurred, induction chemotherapy cleared all manifestations of the illness. Shortly thereafter, while blood and bone marrow remained in remission, the skin lesions reappeared. The introduction of 6‐thioguanine, as part of the maintenance treatment protocol, resulted in the rapid and permanent disappearence of the leukemic skin infiltrates.
ISSN:	0361-8609 1096-8652
DOI:	10.1002/ajh.2830240415