Proteins that bind serotonin in the nervous system of Aplysia californica
The central nervous system of Aplysia has been found to contain two forms of proteins that bind serotonin with high affinity. These proteins share several similarities with the serotonin binding proteins that have been isolated from the vertebrate nervous system. Their ability to bind serotonin is e...
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| Veröffentlicht in: | Neuroscience letters 1987-03, Vol.74 (3), p.257-261 |
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| container_title | Neuroscience letters |
| container_volume | 74 |
| creator | Tamir, H. Liu, K.P. Weiss, K.R. |
| description | The central nervous system of
Aplysia has been found to contain two forms of proteins that bind serotonin with high affinity. These proteins share several similarities with the serotonin binding proteins that have been isolated from the vertebrate nervous system. Their ability to bind serotonin is enhanced by Fe
2+ and inhibited by Na
+,-SH reagents as well as reserpine and
N-acetyl-5-hydroxytryptophyl-5-hydroxytryp-tophanamide. |
| doi_str_mv | 10.1016/0304-3940(87)90306-5 |
| format | Article |
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Aplysia has been found to contain two forms of proteins that bind serotonin with high affinity. These proteins share several similarities with the serotonin binding proteins that have been isolated from the vertebrate nervous system. Their ability to bind serotonin is enhanced by Fe
2+ and inhibited by Na
+,-SH reagents as well as reserpine and
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Aplysia has been found to contain two forms of proteins that bind serotonin with high affinity. These proteins share several similarities with the serotonin binding proteins that have been isolated from the vertebrate nervous system. Their ability to bind serotonin is enhanced by Fe
2+ and inhibited by Na
+,-SH reagents as well as reserpine and
N-acetyl-5-hydroxytryptophyl-5-hydroxytryp-tophanamide.</description><subject>Animals</subject><subject>Aplysia</subject><subject>Aplysia californica</subject><subject>Biological and medical sciences</subject><subject>Carrier Proteins - isolation & purification</subject><subject>Carrier Proteins - metabolism</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Ganglia - analysis</subject><subject>Ganglia - metabolism</subject><subject>Invertebrates</subject><subject>Mollusca</subject><subject>Nerve Tissue Proteins - isolation & purification</subject><subject>Nerve Tissue Proteins - metabolism</subject><subject>Physiology. Development</subject><subject>Protein Binding</subject><subject>Serotonergic neuron</subject><subject>Serotonin</subject><subject>Serotonin - metabolism</subject><subject>Serotonin binding protein</subject><issn>0304-3940</issn><issn>1872-7972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhoMoWj_-gUIOInpYTTabTXIRSvGjIOhBzyGbndDINluTrdB_b2pLjwqBITPPDC8PQueU3FJC6zvCSFUwVZFrKW5U_tUF30MjKkVZCCXKfTTaIUfoOKVPQginvDpEh4zXmVMjNH2L_QA-JDzMzIAbH1qcIPf64APOb5gBDhC_-2XCaZUGmOPe4fGiWyVvsDWdd30M3ppTdOBMl-BsW0_Qx-PD--S5eHl9mk7GL4WtqBgKzpyzprG0bEkDhJaKK9FyxVoplWi4hNI1qimtsCUFIjlriKscuFq1linOTtDV5u4i9l9LSIOe-2Sh60yAHFILUdWsVPW_IM0cFbXMYLUBbexTiuD0Ivq5iStNiV6r1muPeu1RS6F_Vet1kIvt_WUzh3a3tHWb55fbuUnZk4smWJ92mKS0pkxk7H6DQZb27SHqZD0EC62PYAfd9v7vHD_RXZoa</recordid><startdate>19870309</startdate><enddate>19870309</enddate><creator>Tamir, H.</creator><creator>Liu, K.P.</creator><creator>Weiss, K.R.</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19870309</creationdate><title>Proteins that bind serotonin in the nervous system of Aplysia californica</title><author>Tamir, H. ; Liu, K.P. ; Weiss, K.R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-53ffcabc12d0be0129597d593d8897b58e2fb9b2c7c21e0853b0f4fef69dc3953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Animals</topic><topic>Aplysia</topic><topic>Aplysia californica</topic><topic>Biological and medical sciences</topic><topic>Carrier Proteins - isolation & purification</topic><topic>Carrier Proteins - metabolism</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Ganglia - analysis</topic><topic>Ganglia - metabolism</topic><topic>Invertebrates</topic><topic>Mollusca</topic><topic>Nerve Tissue Proteins - isolation & purification</topic><topic>Nerve Tissue Proteins - metabolism</topic><topic>Physiology. Development</topic><topic>Protein Binding</topic><topic>Serotonergic neuron</topic><topic>Serotonin</topic><topic>Serotonin - metabolism</topic><topic>Serotonin binding protein</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tamir, H.</creatorcontrib><creatorcontrib>Liu, K.P.</creatorcontrib><creatorcontrib>Weiss, K.R.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tamir, H.</au><au>Liu, K.P.</au><au>Weiss, K.R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Proteins that bind serotonin in the nervous system of Aplysia californica</atitle><jtitle>Neuroscience letters</jtitle><addtitle>Neurosci Lett</addtitle><date>1987-03-09</date><risdate>1987</risdate><volume>74</volume><issue>3</issue><spage>257</spage><epage>261</epage><pages>257-261</pages><issn>0304-3940</issn><eissn>1872-7972</eissn><coden>NELED5</coden><abstract>The central nervous system of
Aplysia has been found to contain two forms of proteins that bind serotonin with high affinity. These proteins share several similarities with the serotonin binding proteins that have been isolated from the vertebrate nervous system. Their ability to bind serotonin is enhanced by Fe
2+ and inhibited by Na
+,-SH reagents as well as reserpine and
N-acetyl-5-hydroxytryptophyl-5-hydroxytryp-tophanamide.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>3561879</pmid><doi>10.1016/0304-3940(87)90306-5</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0304-3940 |
| ispartof | Neuroscience letters, 1987-03, Vol.74 (3), p.257-261 |
| issn | 0304-3940 1872-7972 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77463296 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals Aplysia Aplysia californica Biological and medical sciences Carrier Proteins - isolation & purification Carrier Proteins - metabolism Fundamental and applied biological sciences. Psychology Ganglia - analysis Ganglia - metabolism Invertebrates Mollusca Nerve Tissue Proteins - isolation & purification Nerve Tissue Proteins - metabolism Physiology. Development Protein Binding Serotonergic neuron Serotonin Serotonin - metabolism Serotonin binding protein |
| title | Proteins that bind serotonin in the nervous system of Aplysia californica |
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