An experimental model to investigate the dynamics of wound contraction

An experimental model to investigate the dynamics of wound contraction

An excisional wound model in the Hooded Lister rat is described. The methods used to inflict, measure and characterise the process of wound contraction are comprehensively discussed. The model is shown to be reliable, reproducible and capable of detecting the effect of systemically administered pred...

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Veröffentlicht in:British journal of plastic surgery 1995-06, Vol.48 (4), p.189-197
Hauptverfasser: Cross, S.E., Naylor, L., Coleman, R.A., Teo, T.C.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biological and medical sciences
Female
Guinea Pigs
Male
Medical sciences
Models, Biological
Prednisolone - pharmacology
Rats
Rats, Inbred Strains
Rats, Sprague-Dawley
Skin - pathology
Skin plastic surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Wound Healing - drug effects
Wound Healing - physiology
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Beschreibung
Zusammenfassung:An excisional wound model in the Hooded Lister rat is described. The methods used to inflict, measure and characterise the process of wound contraction are comprehensively discussed. The model is shown to be reliable, reproducible and capable of detecting the effect of systemically administered prednisolone.
ISSN:0007-1226
1465-3087
DOI:10.1016/0007-1226(95)90001-2