Whipple's disease confined to the central nervous system

Progressive hypersomnia, memory disturbance, and vertical ophthalmoplegia developed in a 63‐year‐old woman. The diagnosis of Whipple's disease of the central nervous system was suggested by her presentation and results of studies using magnetic resonance imaging. Despite a one‐month course of a...

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Veröffentlicht in:	Annals of neurology 1987-01, Vol.21 (1), p.104-108
Hauptverfasser:	Adams, Melanie, Rhyner, Patricia A., Day, John, DeArmond, Stephen, Smuckler, Edward A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - therapeutic use Bacterial diseases Bacterial diseases of the digestive system and abdomen Biological and medical sciences Brain - pathology Central Nervous System Diseases - diagnosis Central Nervous System Diseases - drug therapy Central Nervous System Diseases - pathology Female Human bacterial diseases Humans Infectious diseases Medical sciences Microscopy, Electron Middle Aged Whipple Disease - diagnosis Whipple Disease - drug therapy Whipple Disease - pathology
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Beschreibung
Zusammenfassung:	Progressive hypersomnia, memory disturbance, and vertical ophthalmoplegia developed in a 63‐year‐old woman. The diagnosis of Whipple's disease of the central nervous system was suggested by her presentation and results of studies using magnetic resonance imaging. Despite a one‐month course of antibiotics, active Whipple's disease, localized to the central nervous system, was found at autopsy.
ISSN:	0364-5134 1531-8249
DOI:	10.1002/ana.410210121