Homology between the pyrazine-binding protein from nasal mucosa and major urinary proteins

Homology between the pyrazine-binding protein from nasal mucosa and major urinary proteins

Sequence analysis of the pyrazine-binding protein from bovine olfactory mucosa reveals marked homology with a family of proteins of unknown function found in the urine of the adult male mouse and rat. In view of the dramatic biological responses to odorants transmitted in male rodent urines, it is p...

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Veröffentlicht in:FEBS letters 1987-02, Vol.212 (2), p.225-228
Hauptverfasser: Cavaggioni, A., Sorbi, R.T., Keen, J.N., Pappin, D.J.C., Findlay, J.B.C.
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acid Sequence
Animals
Biological and medical sciences
Carrier Proteins - genetics
Cattle
Fundamental and applied biological sciences. Psychology
General aspects
Nasal Mucosa - metabolism
Odor reception
Odor transmission
Olfaction
Proteins - genetics
Proteinuria
Pyrazine-binding protein
Receptors, Odorant
Vertebrates: respiratory system
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Zusammenfassung:Sequence analysis of the pyrazine-binding protein from bovine olfactory mucosa reveals marked homology with a family of proteins of unknown function found in the urine of the adult male mouse and rat. In view of the dramatic biological responses to odorants transmitted in male rodent urines, it is proposed that these proteins play important roles in some aspects of odor transmission and reception.
ISSN:0014-5793
1873-3468
DOI:10.1016/0014-5793(87)81349-2