Long Term Complete Remission in Primary Plasma Cell Leukemia

A 76-year-old female was diagnosed as having primary plasma cell leukemia (PCL), based on abundant atypical plasma cells in the circulation and bone marrow, monoclonal K light chain in the serum and urine, the immunophenotype of the plasma cells and the lack of preceding multiple myeloma. The patien...

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Veröffentlicht in:	Internal Medicine 1995, Vol.34(4), pp.251-254
Hauptverfasser:	TSUYUOKA, Reiko, TAKAHASHI, Takayuki, SASAKI, Yutaka, NAKAMURA, Kishiko, FUKUMOTO, Manabu, KURISU, Yoshitaka, TSUBAKIMORI, Kumiko, SHIOI, Kouichi, NAKAO, Kazuwa
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Female Hematologic and hematopoietic diseases Humans Leukemia, Plasma Cell - diagnosis Leukemia, Plasma Cell - drug therapy Leukemia, Plasma Cell - metabolism Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Medical sciences melphalan Melphalan - therapeutic use prednisolone Prednisolone - therapeutic use Remission Induction
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Zusammenfassung:	A 76-year-old female was diagnosed as having primary plasma cell leukemia (PCL), based on abundant atypical plasma cells in the circulation and bone marrow, monoclonal K light chain in the serum and urine, the immunophenotype of the plasma cells and the lack of preceding multiple myeloma. The patient was treated with melphalan and prednisolone (MP), and complete remission (CR) was achieved; this was maintained for 28 months. The duration of CR in this patient appears to be the longest of those reported in well-documented primary PCL patients who have been treated with MP chemotherapy. (Internal Medicine 34: 251-254, 1995)
ISSN:	0918-2918 1349-7235
DOI:	10.2169/internalmedicine.34.251